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Absence of 5-HT3 and cholinergic mechanisms in improgan antinociception

  • J.B. Nalwalk
  • , K. Svokos
  • , R. Leurs
  • , L.H. Hough

    Research output: Contribution to JournalArticleAcademicpeer-review

    Abstract

    Improgan, an analgesic derived from histamine antagonists, acts in the brain stem to activate descending non-opioid, pain-relieving circuits, but the mechanism of action of this drug remains elusive. Because improgan has a moderate affinity for 5-HT
    Original languageEnglish
    Pages (from-to)505-510
    JournalPharmacology, Biochemistry and Behavior
    Volume80
    Issue number3
    DOIs
    Publication statusPublished - 2005

    UN SDGs

    This output contributes to the following UN Sustainable Development Goals (SDGs)

    1. SDG 3 - Good Health and Well-being
      SDG 3 Good Health and Well-being

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