Active Site Substitution A82W Improves the Regioselectivity of Steroid Hydroxylation by Cytochrome P450 BM3 Mutants As Rationalized by Spin Relaxation Nuclear Magnetic Resonance Studies

V. Rea, A.J. Kolkman, E.R. Vottero, E.J. Stronks, K.A. Ampt, M. Honing, N.P.E. Vermeulen, S.S. Wijmenga, J.N.M. Commandeur

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