Age-related neural correlates of cognitive task performance under increased postural load

A Van Impe, S M Bruijn, J P Coxon, N Wenderoth, S Sunaert, J Duysens, S P Swinnen

    Research output: Contribution to JournalArticleAcademicpeer-review

    Abstract

    Behavioral studies suggest that postural control requires increased cognitive control and visuospatial processing with aging. Consequently, performance can decline when concurrently performing a postural and a demanding cognitive task. We aimed to identify the neural substrate underlying this effect. A demanding cognitive task, requiring visuospatial transformations, was performed with varying postural loads. More specifically, old and young subjects performed mental rotations of abstract figures in a seated position and when standing on a force platform. Additionally, functional magnetic resonance imaging (fMRI) was used to identify brain regions associated with mental rotation performance. Old as compared to young subjects showed increased blood oxygenation level-dependent (BOLD) responses in a frontoparietal network as well as activations in additional areas. Despite this overall increased activation, they could still modulate BOLD responses with increasing task complexity. Importantly, activity in left lingual gyrus was highly predictive (r = -0.83, adjusted R(2) = 0.65) of the older subjects' degree of success in mental rotation performance when shifting from a sitting to a standing position. More specifically, increased activation in this area was associated with better performance, once postural load increased.

    LanguageEnglish
    Pages2111-24
    Number of pages14
    JournalAge
    Volume35
    Issue number6
    DOIs
    Publication statusPublished - Dec 2013

    Fingerprint

    Task Performance and Analysis
    Posture
    Occipital Lobe
    Magnetic Resonance Imaging
    Brain

    Keywords

    • Adolescent
    • Adult
    • Aged
    • Aged, 80 and over
    • Aging
    • Attention
    • Cognition
    • Female
    • Frontal Lobe
    • Humans
    • Magnetic Resonance Imaging
    • Male
    • Mental Processes
    • Middle Aged
    • Neural Pathways
    • Parietal Lobe
    • Postural Balance
    • Posture
    • Psychomotor Performance
    • Reference Values
    • Task Performance and Analysis
    • Young Adult
    • Journal Article
    • Research Support, Non-U.S. Gov't

    Cite this

    Van Impe, A., Bruijn, S. M., Coxon, J. P., Wenderoth, N., Sunaert, S., Duysens, J., & Swinnen, S. P. (2013). Age-related neural correlates of cognitive task performance under increased postural load. Age, 35(6), 2111-24. https://doi.org/10.1007/s11357-012-9499-2
    Van Impe, A ; Bruijn, S M ; Coxon, J P ; Wenderoth, N ; Sunaert, S ; Duysens, J ; Swinnen, S P. / Age-related neural correlates of cognitive task performance under increased postural load. In: Age. 2013 ; Vol. 35, No. 6. pp. 2111-24.
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    abstract = "Behavioral studies suggest that postural control requires increased cognitive control and visuospatial processing with aging. Consequently, performance can decline when concurrently performing a postural and a demanding cognitive task. We aimed to identify the neural substrate underlying this effect. A demanding cognitive task, requiring visuospatial transformations, was performed with varying postural loads. More specifically, old and young subjects performed mental rotations of abstract figures in a seated position and when standing on a force platform. Additionally, functional magnetic resonance imaging (fMRI) was used to identify brain regions associated with mental rotation performance. Old as compared to young subjects showed increased blood oxygenation level-dependent (BOLD) responses in a frontoparietal network as well as activations in additional areas. Despite this overall increased activation, they could still modulate BOLD responses with increasing task complexity. Importantly, activity in left lingual gyrus was highly predictive (r = -0.83, adjusted R(2) = 0.65) of the older subjects' degree of success in mental rotation performance when shifting from a sitting to a standing position. More specifically, increased activation in this area was associated with better performance, once postural load increased.",
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    Van Impe, A, Bruijn, SM, Coxon, JP, Wenderoth, N, Sunaert, S, Duysens, J & Swinnen, SP 2013, 'Age-related neural correlates of cognitive task performance under increased postural load', Age, vol. 35, no. 6, pp. 2111-24. https://doi.org/10.1007/s11357-012-9499-2

    Age-related neural correlates of cognitive task performance under increased postural load. / Van Impe, A; Bruijn, S M; Coxon, J P; Wenderoth, N; Sunaert, S; Duysens, J; Swinnen, S P.

    In: Age, Vol. 35, No. 6, 12.2013, p. 2111-24.

    Research output: Contribution to JournalArticleAcademicpeer-review

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    AU - Bruijn, S M

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    AU - Duysens, J

    AU - Swinnen, S P

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    AB - Behavioral studies suggest that postural control requires increased cognitive control and visuospatial processing with aging. Consequently, performance can decline when concurrently performing a postural and a demanding cognitive task. We aimed to identify the neural substrate underlying this effect. A demanding cognitive task, requiring visuospatial transformations, was performed with varying postural loads. More specifically, old and young subjects performed mental rotations of abstract figures in a seated position and when standing on a force platform. Additionally, functional magnetic resonance imaging (fMRI) was used to identify brain regions associated with mental rotation performance. Old as compared to young subjects showed increased blood oxygenation level-dependent (BOLD) responses in a frontoparietal network as well as activations in additional areas. Despite this overall increased activation, they could still modulate BOLD responses with increasing task complexity. Importantly, activity in left lingual gyrus was highly predictive (r = -0.83, adjusted R(2) = 0.65) of the older subjects' degree of success in mental rotation performance when shifting from a sitting to a standing position. More specifically, increased activation in this area was associated with better performance, once postural load increased.

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    KW - Reference Values

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    KW - Journal Article

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    ER -