Abstract
PURPOSE: In 1998, the AIDS Therapy Evaluation in the Netherlands (ATHENA) national observational HIV cohort was established to demonstrate the lifesaving effectiveness of triple combination antiretroviral therapy, including HIV-protease inhibitors, that had recently been made available for clinical use. Subsequently, the HIV Monitoring Foundation was established by the Dutch Ministry of Health, Welfare and Sport to continue ATHENA as an open cohort in order to continue the registration and monitoring of all HIV-positive people as an integral part of HIV care in all 26 HIV treatment centres in the Netherlands.
PARTICIPANTS: To date, a total of 25 036 participants have been enrolled in the cohort, with 263 600 person-years of follow-up. As of 1 January 2017, 19 035 HIV-1-positive participants were known to be in care: 18 824 adults (81% men and 19% women) and 211 children (47% boys and 53% girls). The remaining 6001 participants had either died (46%), were lost to care (29%) or had moved abroad (25%).
FINDINGS TO DATE: Today, with over 20 years of follow-up, the ATHENA cohort has provided extensive knowledge on HIV treatment, comorbidities and coinfections and created insight into the transmission dynamics of the HIV epidemic.
FUTURE PLANS: ATHENA continues to enrol and monitor HIV positive people entering HIV care in the Netherlands. Future research will continue to provide tangible input into HIV care and prevention policies in the Netherlands and internationally.
| Original language | English |
|---|---|
| Article number | e022522 |
| Pages (from-to) | e022516 |
| Journal | BMJ Open |
| Volume | 8 |
| Issue number | 9 |
| DOIs | |
| Publication status | Published - 24 Sept 2018 |
Bibliographical note
© Author(s) (or their employer(s)) 2018. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.Funding
Funding The ATHENA cohort is managed by Stichting HIV Monitoring and supported by a grant from the Dutch Ministry of Health, Welfare and Sport through the Centre for Infectious Disease Control of the National Institute for Public Health and the Environment.
| Funders |
|---|
| National Institute for Public Health and the Environment |
| Ministerie van Volksgezondheid, Welzijn en Sport |
Keywords
- Adult
- Antiretroviral Therapy, Highly Active/methods
- Child
- Cohort Studies
- Drug Monitoring/methods
- Female
- HIV Infections/drug therapy
- Humans
- Male
- Netherlands/epidemiology
- Outcome and Process Assessment, Health Care
- Patient Care Management/organization & administration
- Treatment Outcome
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