An Odyssey towards personalised medicine in breast cancer: From discovering new cancer genes to revealing drivers of therapeutic resistance

G.J. Ikink

An Odyssey towards personalised medicine in breast cancer: From discovering new cancer genes to revealing drivers of therapeutic resistance

G.J. Ikink

Research output: PhD Thesis › PhD-Thesis - Research and graduation internal

554 Downloads (Pure)

Original language	English
Qualification	PhD
Awarding Institution	Vrije Universiteit Amsterdam
Supervisors/Advisors	Peeper, D.S., Supervisor, External person Hilkens, J., Co-supervisor, External person
Award date	28 Sep 2018
Print ISBNs	9789075575491
Publication status	Published - 2018

Keywords

Personalised medicine; Breast cancer; Therapy resistance; Oncogenes; Molecular Biology; Genetics

Access to Document

CoverFinal published version, 444 KB
Title pageFinal published version, 46.4 KB
Abstract dutchFinal published version, 135 KB
Abstract englishFinal published version, 79.4 KB
Table of contentsFinal published version, 38.9 KB
Complete dissertationFinal published version, 16.1 MB
Chapter 1 - General IntroductionFinal published version, 2 MB
Chapter 2 - ERAS in HER2 positive breast cancer insertional mutagenesis screensFinal published version, 3.48 MB
Chapter 3 - IRS4 drives cancer by PI3K/AKT/mTOR pathway hyperactivationFinal published version, 5.91 MB
Chapter 4 - IRS4 and ERAS induce resistance to HER2 targeted therapyFinal published version, 3.01 MB
Chapter 5 - General DiscussionFinal published version, 687 KB

Handle.net

Persistent link

Cite this

@phdthesis{e5a6de2bad7a46d99f9471d6213d7d7c,

title = "An Odyssey towards personalised medicine in breast cancer: From discovering new cancer genes to revealing drivers of therapeutic resistance",

keywords = "Personalised medicine; Breast cancer; Therapy resistance; Oncogenes; Molecular Biology; Genetics",

author = "G.J. Ikink",

year = "2018",

language = "English",

isbn = "9789075575491 ",

school = "Vrije Universiteit Amsterdam",

}

TY - THES

T1 - An Odyssey towards personalised medicine in breast cancer

T2 - From discovering new cancer genes to revealing drivers of therapeutic resistance

AU - Ikink, G.J.

PY - 2018

Y1 - 2018

KW - Personalised medicine; Breast cancer; Therapy resistance; Oncogenes; Molecular Biology; Genetics

M3 - PhD-Thesis - Research and graduation internal

SN - 9789075575491

ER -