TY - JOUR
T1 - Analysis of perfluorinated compounds in biota by microextraction with tetrahydrofuran and liquid chromatography/ion isolation-based ion-trap mass spectrometry
AU - Luque, N.
AU - Ballesteros-Gómez, A.
AU - van Leeuwen, S.P.J.
AU - Rubio, S.
N1 - J 1
PY - 2010
Y1 - 2010
N2 - An analytical method combining both a simple, fast and efficient solvent microextraction and a sensitive and selective monitoring mode, based on ion isolation ion-trap mass spectrometry (MS), was developed for analysis of perfluorinated compounds (PFCs) in biota. The method involved the vortex-shaking of 0.2g of tissue sample and 800μL of tetrahydrofuran (THF):water (75:25, v/v) for 7min, subsequent centrifugation for 13min and direct quantitation of PFCs in the extract against solvent-based calibration curves. Selection of solvent composition was based on Hildebrand solubility parameters and their components (i.e. dispersion, dipole-dipole and hydrogen bonding forces). Recoveries in samples for PFCs with hydrocarbon chain lengths between C
AB - An analytical method combining both a simple, fast and efficient solvent microextraction and a sensitive and selective monitoring mode, based on ion isolation ion-trap mass spectrometry (MS), was developed for analysis of perfluorinated compounds (PFCs) in biota. The method involved the vortex-shaking of 0.2g of tissue sample and 800μL of tetrahydrofuran (THF):water (75:25, v/v) for 7min, subsequent centrifugation for 13min and direct quantitation of PFCs in the extract against solvent-based calibration curves. Selection of solvent composition was based on Hildebrand solubility parameters and their components (i.e. dispersion, dipole-dipole and hydrogen bonding forces). Recoveries in samples for PFCs with hydrocarbon chain lengths between C
U2 - 10.1016/j.chroma.2010.04.014
DO - 10.1016/j.chroma.2010.04.014
M3 - Article
VL - 1217
SP - 3774
EP - 3782
JO - Journal of chromatography A
JF - Journal of chromatography A
SN - 0021-9673
IS - 24
ER -
