Analysis of perfluorinated compounds in biota by microextraction with tetrahydrofuran and liquid chromatography/ion isolation-based ion-trap mass spectrometry

N. Luque; A. Ballesteros-Gómez; S.P.J. van Leeuwen; S. Rubio

doi:10.1016/j.chroma.2010.04.014

Analysis of perfluorinated compounds in biota by microextraction with tetrahydrofuran and liquid chromatography/ion isolation-based ion-trap mass spectrometry

N. Luque
, A. Ballesteros-Gómez
, S.P.J. van Leeuwen
, S. Rubio

Chemistry and Biology

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

An analytical method combining both a simple, fast and efficient solvent microextraction and a sensitive and selective monitoring mode, based on ion isolation ion-trap mass spectrometry (MS), was developed for analysis of perfluorinated compounds (PFCs) in biota. The method involved the vortex-shaking of 0.2g of tissue sample and 800μL of tetrahydrofuran (THF):water (75:25, v/v) for 7min, subsequent centrifugation for 13min and direct quantitation of PFCs in the extract against solvent-based calibration curves. Selection of solvent composition was based on Hildebrand solubility parameters and their components (i.e. dispersion, dipole-dipole and hydrogen bonding forces). Recoveries in samples for PFCs with hydrocarbon chain lengths between C

Original language	English
Pages (from-to)	3774-3782
Journal	Journal of Chromatography A
Volume	1217
Issue number	24
DOIs	https://doi.org/10.1016/j.chroma.2010.04.014
Publication status	Published - 2010

Bibliographical note

J 1

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This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 6 Clean Water and Sanitation

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10.1016/j.chroma.2010.04.014

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title = "Analysis of perfluorinated compounds in biota by microextraction with tetrahydrofuran and liquid chromatography/ion isolation-based ion-trap mass spectrometry",

abstract = "An analytical method combining both a simple, fast and efficient solvent microextraction and a sensitive and selective monitoring mode, based on ion isolation ion-trap mass spectrometry (MS), was developed for analysis of perfluorinated compounds (PFCs) in biota. The method involved the vortex-shaking of 0.2g of tissue sample and 800μL of tetrahydrofuran (THF):water (75:25, v/v) for 7min, subsequent centrifugation for 13min and direct quantitation of PFCs in the extract against solvent-based calibration curves. Selection of solvent composition was based on Hildebrand solubility parameters and their components (i.e. dispersion, dipole-dipole and hydrogen bonding forces). Recoveries in samples for PFCs with hydrocarbon chain lengths between C",

author = "N. Luque and A. Ballesteros-G{\'o}mez and \{van Leeuwen\}, S.P.J. and S. Rubio",

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doi = "10.1016/j.chroma.2010.04.014",

language = "English",

volume = "1217",

pages = "3774--3782",

journal = "Journal of Chromatography A",

issn = "0021-9673",

publisher = "Elsevier B.V.",

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}

Analysis of perfluorinated compounds in biota by microextraction with tetrahydrofuran and liquid chromatography/ion isolation-based ion-trap mass spectrometry. / Luque, N.; Ballesteros-Gómez, A.; van Leeuwen, S.P.J. et al.
In: Journal of Chromatography A, Vol. 1217, No. 24, 2010, p. 3774-3782.

Research output: Contribution to Journal › Article › Academic › peer-review

TY - JOUR

T1 - Analysis of perfluorinated compounds in biota by microextraction with tetrahydrofuran and liquid chromatography/ion isolation-based ion-trap mass spectrometry

AU - Luque, N.

AU - Ballesteros-Gómez, A.

AU - van Leeuwen, S.P.J.

AU - Rubio, S.

N1 - J 1

PY - 2010

Y1 - 2010

N2 - An analytical method combining both a simple, fast and efficient solvent microextraction and a sensitive and selective monitoring mode, based on ion isolation ion-trap mass spectrometry (MS), was developed for analysis of perfluorinated compounds (PFCs) in biota. The method involved the vortex-shaking of 0.2g of tissue sample and 800μL of tetrahydrofuran (THF):water (75:25, v/v) for 7min, subsequent centrifugation for 13min and direct quantitation of PFCs in the extract against solvent-based calibration curves. Selection of solvent composition was based on Hildebrand solubility parameters and their components (i.e. dispersion, dipole-dipole and hydrogen bonding forces). Recoveries in samples for PFCs with hydrocarbon chain lengths between C

AB - An analytical method combining both a simple, fast and efficient solvent microextraction and a sensitive and selective monitoring mode, based on ion isolation ion-trap mass spectrometry (MS), was developed for analysis of perfluorinated compounds (PFCs) in biota. The method involved the vortex-shaking of 0.2g of tissue sample and 800μL of tetrahydrofuran (THF):water (75:25, v/v) for 7min, subsequent centrifugation for 13min and direct quantitation of PFCs in the extract against solvent-based calibration curves. Selection of solvent composition was based on Hildebrand solubility parameters and their components (i.e. dispersion, dipole-dipole and hydrogen bonding forces). Recoveries in samples for PFCs with hydrocarbon chain lengths between C

U2 - 10.1016/j.chroma.2010.04.014

DO - 10.1016/j.chroma.2010.04.014

M3 - Article

SN - 0021-9673

VL - 1217

SP - 3774

EP - 3782

JO - Journal of Chromatography A

JF - Journal of Chromatography A

IS - 24

ER -

Analysis of perfluorinated compounds in biota by microextraction with tetrahydrofuran and liquid chromatography/ion isolation-based ion-trap mass spectrometry

Abstract

Bibliographical note

UN SDGs

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