TY - JOUR
T1 - Analyte-deposition-based detection in column liquid chromatography: concept and examples.
AU - Gooijer, C.
AU - Brinkman, U.A.T.
AU - Somsen, G.W.
PY - 1998
Y1 - 1998
N2 - Column liquid chromatography (LC) is a powerful tool for the separation of constituents of complex mixtures and it can handle a wide range of sample types and analyte classes. Today, the on-line combination of LC and a spectrometric detection technique for analyte quantification as well as identification purposes is a powerful and well-known approach. However, there are also situations in which the separation and detection conditions are not at all compatible. Semi on-line coupling via intermediate analyte deposition on a suitable substrate then offers an elegant solution, as will be described in some detail in the present review.
AB - Column liquid chromatography (LC) is a powerful tool for the separation of constituents of complex mixtures and it can handle a wide range of sample types and analyte classes. Today, the on-line combination of LC and a spectrometric detection technique for analyte quantification as well as identification purposes is a powerful and well-known approach. However, there are also situations in which the separation and detection conditions are not at all compatible. Semi on-line coupling via intermediate analyte deposition on a suitable substrate then offers an elegant solution, as will be described in some detail in the present review.
U2 - 10.1016/S0165-9936(98)00005-3
DO - 10.1016/S0165-9936(98)00005-3
M3 - Article
VL - 17
SP - 129
JO - TrAC. Trends in Analytical Chemistry
JF - TrAC. Trends in Analytical Chemistry
SN - 0165-9936
ER -
