Abstract
Column liquid chromatography (LC) is a powerful tool for the separation of constituents of complex mixtures and it can handle a wide range of sample types and analyte classes. Today, the on-line combination of LC and a spectrometric detection technique for analyte quantification as well as identification purposes is a powerful and well-known approach. However, there are also situations in which the separation and detection conditions are not at all compatible. Semi on-line coupling via intermediate analyte deposition on a suitable substrate then offers an elegant solution, as will be described in some detail in the present review.
Original language | English |
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Pages (from-to) | 129 |
Journal | TrAC. Trends in Analytical Chemistry |
Volume | 17 |
DOIs | |
Publication status | Published - 1998 |