Family supportive supervision has emerged as an important prerequisite for effective work-family integration and employees' well-being. Scholars are addressing the need to develop family supportive managers and have introduced a new construct and measure, 'family supportive supervisor behavior'. So far, little attention has been focused on the underlying behavioral process and managerial characteristics that triggers family supportive supervisor behavior. In response, a multilevel conceptual framework is developed that identifies individual-level and contextual-level factors that would predict managers' overall tendency to engage in family supportive supervisor behavior. The consequences of family supportive supervisor behavior on organizational outcomes such as the subordinate and the team level and its practical implications are outlined. In presenting a multilevel conceptual framework for family supportive supervisor behavior, a research agenda is proposed that can guide future researchers in the field of family supportive supervision. © 2011 Elsevier Inc.