Association of Adiposity Genetic Variants With Menarche Timing in 92,105 Women of European Descent

L. Fernández-Rhodes; E.W. Demerath; D.L. Cousminer; R. Tao; J.G. Dreyfus; T. Esko; A.V. Smith; V. Gudnason; T.B. Harris; L. Launer; P.F. McArdle; L.M. Yerges-Armstrong; C.E. Elks; D.P. Strachan; Z. Kutalik; P. Vollenweider; B. Feenstra; H.A. Boyd; A. Metspalu; E. Mihailov; L. Broer; M.C. Zillikens; B.A. Oostra; C.M. van Duijn; K.L. Lunetta; J.R. Perry; A. Murray; D.L. Koller; D. Lai; T. Corre; D. Toniolo; E. Albrecht; D. Stöckl; H. Grallert; C. Gieger; C. Hayward; O. Polasek; I. Rudan; J.F. Wilson; C. He; P. Kraft; F.B. Hu; D.J. Hunter; J.J. Hottenga; G. Willemsen; D.I. Boomsma; E.M. Byrne; N.G. Martin; G.W. Montgomery; N.M. Warrington; C.E. Pennell; L. Stolk; J.A. Visser; A. Hofman; A.G. Uitterlinden; F. Rivadeneira; P. Lin; S.L. Fisher; L.J. Bierut; L. Crisponi; E. Porcu; M. Mangino; G. Zhai; T.D. Spector; J.E. Buring; L.M. Rose; P.M. Ridker; C. Poole; J.N. Hirschhorn; J.M. Murabito; D.I. Chasman; E. Widén; K.E. North; K.K. Ong; N. Franceschini

doi:10.1093/aje/kws473

Association of Adiposity Genetic Variants With Menarche Timing in 92,105 Women of European Descent

L. Fernández-Rhodes
, E.W. Demerath
, D.L. Cousminer
, R. Tao
, J.G. Dreyfus
, T. Esko
, A.V. Smith
, V. Gudnason
, T.B. Harris
, L. Launer
, P.F. McArdle
, L.M. Yerges-Armstrong
, C.E. Elks
, D.P. Strachan
, Z. Kutalik
, P. Vollenweider
, B. Feenstra
, H.A. Boyd
, A. Metspalu
, E. Mihailov

L. Broer, M.C. Zillikens, B.A. Oostra, C.M. van Duijn, K.L. Lunetta, J.R. Perry, A. Murray, D.L. Koller, D. Lai, T. Corre, D. Toniolo, E. Albrecht, D. Stöckl, H. Grallert, C. Gieger, C. Hayward, O. Polasek, I. Rudan, J.F. Wilson, C. He, P. Kraft, F.B. Hu, D.J. Hunter, J.J. Hottenga, G. Willemsen, D.I. Boomsma, E.M. Byrne, N.G. Martin, G.W. Montgomery, N.M. Warrington, C.E. Pennell, L. Stolk, J.A. Visser, A. Hofman, A.G. Uitterlinden, F. Rivadeneira, P. Lin, S.L. Fisher, L.J. Bierut, L. Crisponi, E. Porcu, M. Mangino, G. Zhai, T.D. Spector, J.E. Buring, L.M. Rose, P.M. Ridker, C. Poole, J.N. Hirschhorn, J.M. Murabito, D.I. Chasman, E. Widén, K.E. North, K.K. Ong, N. Franceschini

Biological Psychology

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

Obesity is of global health concern. There are well-described inverse relationships between female pubertal timing and obesity. Recent genome-wide association studies of age at menarche identified several obesity-related variants. Using data from the ReproGen Consortium, we employed meta-analytical techniques to estimate the associations of 95 a priori and recently identified obesity-related (body mass index (weight (kg)/height (m)

Original language	English
Pages (from-to)	451-460
Journal	American Journal of Epidemiology
Volume	178
Issue number	3
DOIs	https://doi.org/10.1093/aje/kws473
Publication status	Published - 2013

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This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Cohort Studies

Netherlands Twin Register (NTR)

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10.1093/aje/kws473

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Fernández-Rhodes, L., Demerath, E. W., Cousminer, D. L., Tao, R., Dreyfus, J. G., Esko, T., Smith, A. V., Gudnason, V., Harris, T. B., Launer, L., McArdle, P. F., Yerges-Armstrong, L. M., Elks, C. E., Strachan, D. P., Kutalik, Z., Vollenweider, P., Feenstra, B., Boyd, H. A., Metspalu, A., ... Franceschini, N. (2013). Association of Adiposity Genetic Variants With Menarche Timing in 92,105 Women of European Descent. American Journal of Epidemiology, 178(3), 451-460. https://doi.org/10.1093/aje/kws473

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title = "Association of Adiposity Genetic Variants With Menarche Timing in 92,105 Women of European Descent",

abstract = "Obesity is of global health concern. There are well-described inverse relationships between female pubertal timing and obesity. Recent genome-wide association studies of age at menarche identified several obesity-related variants. Using data from the ReproGen Consortium, we employed meta-analytical techniques to estimate the associations of 95 a priori and recently identified obesity-related (body mass index (weight (kg)/height (m)",

author = "L. Fern{\'a}ndez-Rhodes and E.W. Demerath and D.L. Cousminer and R. Tao and J.G. Dreyfus and T. Esko and A.V. Smith and V. Gudnason and T.B. Harris and L. Launer and P.F. McArdle and L.M. Yerges-Armstrong and C.E. Elks and D.P. Strachan and Z. Kutalik and P. Vollenweider and B. Feenstra and H.A. Boyd and A. Metspalu and E. Mihailov and L. Broer and M.C. Zillikens and B.A. Oostra and \{van Duijn\}, C.M. and K.L. Lunetta and J.R. Perry and A. Murray and D.L. Koller and D. Lai and T. Corre and D. Toniolo and E. Albrecht and D. St{\"o}ckl and H. Grallert and C. Gieger and C. Hayward and O. Polasek and I. Rudan and J.F. Wilson and C. He and P. Kraft and F.B. Hu and D.J. Hunter and J.J. Hottenga and G. Willemsen and D.I. Boomsma and E.M. Byrne and N.G. Martin and G.W. Montgomery and N.M. Warrington and C.E. Pennell and L. Stolk and J.A. Visser and A. Hofman and A.G. Uitterlinden and F. Rivadeneira and P. Lin and S.L. Fisher and L.J. Bierut and L. Crisponi and E. Porcu and M. Mangino and G. Zhai and T.D. Spector and J.E. Buring and L.M. Rose and P.M. Ridker and C. Poole and J.N. Hirschhorn and J.M. Murabito and D.I. Chasman and E. Wid{\'e}n and K.E. North and K.K. Ong and N. Franceschini",

year = "2013",

doi = "10.1093/aje/kws473",

language = "English",

volume = "178",

pages = "451--460",

journal = "American Journal of Epidemiology",

issn = "0002-9262",

publisher = "Oxford University Press",

number = "3",

}

Fernández-Rhodes, L, Demerath, EW, Cousminer, DL, Tao, R, Dreyfus, JG, Esko, T, Smith, AV, Gudnason, V, Harris, TB, Launer, L, McArdle, PF, Yerges-Armstrong, LM, Elks, CE, Strachan, DP, Kutalik, Z, Vollenweider, P, Feenstra, B, Boyd, HA, Metspalu, A, Mihailov, E, Broer, L, Zillikens, MC, Oostra, BA, van Duijn, CM, Lunetta, KL, Perry, JR, Murray, A, Koller, DL, Lai, D, Corre, T, Toniolo, D, Albrecht, E, Stöckl, D, Grallert, H, Gieger, C, Hayward, C, Polasek, O, Rudan, I, Wilson, JF, He, C, Kraft, P, Hu, FB, Hunter, DJ, Hottenga, JJ, Willemsen, G, Boomsma, DI, Byrne, EM, Martin, NG, Montgomery, GW, Warrington, NM, Pennell, CE, Stolk, L, Visser, JA, Hofman, A, Uitterlinden, AG, Rivadeneira, F, Lin, P, Fisher, SL, Bierut, LJ, Crisponi, L, Porcu, E, Mangino, M, Zhai, G, Spector, TD, Buring, JE, Rose, LM, Ridker, PM, Poole, C, Hirschhorn, JN, Murabito, JM, Chasman, DI, Widén, E, North, KE, Ong, KK & Franceschini, N 2013, 'Association of Adiposity Genetic Variants With Menarche Timing in 92,105 Women of European Descent', American Journal of Epidemiology, vol. 178, no. 3, pp. 451-460. https://doi.org/10.1093/aje/kws473

TY - JOUR

T1 - Association of Adiposity Genetic Variants With Menarche Timing in 92,105 Women of European Descent

AU - Fernández-Rhodes, L.

AU - Demerath, E.W.

AU - Cousminer, D.L.

AU - Tao, R.

AU - Dreyfus, J.G.

AU - Esko, T.

AU - Smith, A.V.

AU - Gudnason, V.

AU - Harris, T.B.

AU - Launer, L.

AU - McArdle, P.F.

AU - Yerges-Armstrong, L.M.

AU - Elks, C.E.

AU - Strachan, D.P.

AU - Kutalik, Z.

AU - Vollenweider, P.

AU - Feenstra, B.

AU - Boyd, H.A.

AU - Metspalu, A.

AU - Mihailov, E.

AU - Broer, L.

AU - Zillikens, M.C.

AU - Oostra, B.A.

AU - van Duijn, C.M.

AU - Lunetta, K.L.

AU - Perry, J.R.

AU - Murray, A.

AU - Koller, D.L.

AU - Lai, D.

AU - Corre, T.

AU - Toniolo, D.

AU - Albrecht, E.

AU - Stöckl, D.

AU - Grallert, H.

AU - Gieger, C.

AU - Hayward, C.

AU - Polasek, O.

AU - Rudan, I.

AU - Wilson, J.F.

AU - He, C.

AU - Kraft, P.

AU - Hu, F.B.

AU - Hunter, D.J.

AU - Hottenga, J.J.

AU - Willemsen, G.

AU - Boomsma, D.I.

AU - Byrne, E.M.

AU - Martin, N.G.

AU - Montgomery, G.W.

AU - Warrington, N.M.

AU - Pennell, C.E.

AU - Stolk, L.

AU - Visser, J.A.

AU - Hofman, A.

AU - Uitterlinden, A.G.

AU - Rivadeneira, F.

AU - Lin, P.

AU - Fisher, S.L.

AU - Bierut, L.J.

AU - Crisponi, L.

AU - Porcu, E.

AU - Mangino, M.

AU - Zhai, G.

AU - Spector, T.D.

AU - Buring, J.E.

AU - Rose, L.M.

AU - Ridker, P.M.

AU - Poole, C.

AU - Hirschhorn, J.N.

AU - Murabito, J.M.

AU - Chasman, D.I.

AU - Widén, E.

AU - North, K.E.

AU - Ong, K.K.

AU - Franceschini, N.

PY - 2013

Y1 - 2013

N2 - Obesity is of global health concern. There are well-described inverse relationships between female pubertal timing and obesity. Recent genome-wide association studies of age at menarche identified several obesity-related variants. Using data from the ReproGen Consortium, we employed meta-analytical techniques to estimate the associations of 95 a priori and recently identified obesity-related (body mass index (weight (kg)/height (m)

AB - Obesity is of global health concern. There are well-described inverse relationships between female pubertal timing and obesity. Recent genome-wide association studies of age at menarche identified several obesity-related variants. Using data from the ReproGen Consortium, we employed meta-analytical techniques to estimate the associations of 95 a priori and recently identified obesity-related (body mass index (weight (kg)/height (m)

U2 - 10.1093/aje/kws473

DO - 10.1093/aje/kws473

M3 - Article

SN - 0002-9262

VL - 178

SP - 451

EP - 460

JO - American Journal of Epidemiology

JF - American Journal of Epidemiology

IS - 3

ER -

Association of Adiposity Genetic Variants With Menarche Timing in 92,105 Women of European Descent

Abstract

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