Bacterial proteases: targets for diagnostics and therapy

W.E. Kaman; J.P. Hays; H.P. Endtz; F.J. Bikker

doi:10.1007/s10096-014-2075-1

Bacterial proteases: targets for diagnostics and therapy

W.E. Kaman, J.P. Hays, H.P. Endtz, F.J. Bikker

Oral Biochemistry

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

Proteases are essential for the proliferation and growth of bacteria, and are also known to contribute to bacterial virulence. This makes them interesting candidates as diagnostic and therapeutic targets for infectious diseases. In this review, the authors discuss the most recent developments and potential applications for bacterial proteases in the diagnosis and treatment of bacterial infections. Current and future bacterial protease targets are described and their limitations outlined.

Original language	English
Pages (from-to)	1081-1087
Journal	European journal of clinical microbiology & infectious diseases
Volume	33
Issue number	7
DOIs	https://doi.org/10.1007/s10096-014-2075-1
Publication status	Published - 2014

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10.1007/s10096-014-2075-1

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title = "Bacterial proteases: targets for diagnostics and therapy",

abstract = "Proteases are essential for the proliferation and growth of bacteria, and are also known to contribute to bacterial virulence. This makes them interesting candidates as diagnostic and therapeutic targets for infectious diseases. In this review, the authors discuss the most recent developments and potential applications for bacterial proteases in the diagnosis and treatment of bacterial infections. Current and future bacterial protease targets are described and their limitations outlined.",

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AU - Hays, J.P.

AU - Endtz, H.P.

AU - Bikker, F.J.

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AB - Proteases are essential for the proliferation and growth of bacteria, and are also known to contribute to bacterial virulence. This makes them interesting candidates as diagnostic and therapeutic targets for infectious diseases. In this review, the authors discuss the most recent developments and potential applications for bacterial proteases in the diagnosis and treatment of bacterial infections. Current and future bacterial protease targets are described and their limitations outlined.

U2 - 10.1007/s10096-014-2075-1

DO - 10.1007/s10096-014-2075-1

M3 - Article

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EP - 1087

JO - European journal of clinical microbiology & infectious diseases

JF - European journal of clinical microbiology & infectious diseases

IS - 7

ER -

Bacterial proteases: targets for diagnostics and therapy

Abstract

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