BCL2L1 has a functional role in colorectal cancer and its protein expression is associated with chromosome 20q gain

A.H. Sillars-Hardebol; B. Carvalho; J.A.M. Belien; M. de Wit; P.M. Delis-van Diemen; M. Tijssen; M.A. van de Wiel; F. Ponten; R.J.A. Fijneman; G.A. Meijer

doi:10.1002/path.2983

BCL2L1 has a functional role in colorectal cancer and its protein expression is associated with chromosome 20q gain

A.H. Sillars-Hardebol, B. Carvalho, J.A.M. Belien, M. de Wit, P.M. Delis-van Diemen, M. Tijssen, M.A. van de Wiel, F. Ponten, R.J.A. Fijneman, G.A. Meijer

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

Colorectal cancer (CRC) is the second leading cause of cancer death in the western world. The majority of CRCs, which develop from adenoma precursor lesions, show gain of chromosome arm 20q, where BCL2L1 is located. BCL2L1 is an important apoptosis regulating gene that codes for both an anti-apoptotic (Bcl-x

Original language	English
Pages (from-to)	442-450
Journal	Journal of Pathology
Volume	226
Issue number	3
Early online date	18 Aug 2011
DOIs	https://doi.org/10.1002/path.2983
Publication status	Published - 2012

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Sillars-Hardebol, A. H., Carvalho, B., Belien, J. A. M., de Wit, M., Delis-van Diemen, P. M., Tijssen, M., van de Wiel, M. A., Ponten, F., Fijneman, R. J. A., & Meijer, G. A. (2012). BCL2L1 has a functional role in colorectal cancer and its protein expression is associated with chromosome 20q gain. Journal of Pathology, 226(3), 442-450. https://doi.org/10.1002/path.2983

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abstract = "Colorectal cancer (CRC) is the second leading cause of cancer death in the western world. The majority of CRCs, which develop from adenoma precursor lesions, show gain of chromosome arm 20q, where BCL2L1 is located. BCL2L1 is an important apoptosis regulating gene that codes for both an anti-apoptotic (Bcl-x",

author = "A.H. Sillars-Hardebol and B. Carvalho and J.A.M. Belien and {de Wit}, M. and {Delis-van Diemen}, P.M. and M. Tijssen and {van de Wiel}, M.A. and F. Ponten and R.J.A. Fijneman and G.A. Meijer",

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AU - Sillars-Hardebol, A.H.

AU - Carvalho, B.

AU - Belien, J.A.M.

AU - de Wit, M.

AU - Delis-van Diemen, P.M.

AU - Tijssen, M.

AU - van de Wiel, M.A.

AU - Ponten, F.

AU - Fijneman, R.J.A.

AU - Meijer, G.A.

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AB - Colorectal cancer (CRC) is the second leading cause of cancer death in the western world. The majority of CRCs, which develop from adenoma precursor lesions, show gain of chromosome arm 20q, where BCL2L1 is located. BCL2L1 is an important apoptosis regulating gene that codes for both an anti-apoptotic (Bcl-x

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DO - 10.1002/path.2983

M3 - Article

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JO - Journal of Pathology

JF - Journal of Pathology

IS - 3

ER -

BCL2L1 has a functional role in colorectal cancer and its protein expression is associated with chromosome 20q gain

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