Behavioural activation by mental health nurses for late-life depression in primary care: A randomized controlled trial

Noortje Janssen, Marcus J.H. Huibers, Peter L B J Lucassen, Richard Oude Voshaar, Harm W J van Marwijk, Judith Bosmans, Mirjam Pijnappels, Jan Spijker, Gert Jan Hendriks

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

Background: Depressive symptoms are common in older adults. The effectiveness of pharmacological treatments and the availability of psychological treatments in primary care are limited. A behavioural approach to depression treatment might be beneficial to many older adults but such care is still largely unavailable. Behavioural Activation (BA) protocols are less complicated and more easy to train than other psychological therapies, making them very suitable for delivery by less specialised therapists. The recent introduction of the mental health nurse in primary care centres in the Netherlands has created major opportunities for improving the accessibility of psychological treatments for late-life depression in primary care. BA may thus address the needs of older patients while improving treatment outcome and lowering costs.The primary objective of this study is to compare the effectiveness and cost-effectiveness of BA in comparison with treatment as usual (TAU) for late-life depression in Dutch primary care. A secondary goal is to explore several potential mechanisms of change, as well as predictors and moderators of treatment outcome of BA for late-life depression. Methods/design: Cluster-randomised controlled multicentre trial with two parallel groups: a) behavioural activation, and b) treatment as usual, conducted in primary care centres with a follow-up of 52 weeks. The main inclusion criterion is a PHQ-9 score > 9. Patients are excluded from the trial in case of severe mental illness that requires specialized treatment, high suicide risk, drug and/or alcohol abuse, prior psychotherapy, change in dosage or type of prescribed antidepressants in the previous 12 weeks, or moderate to severe cognitive impairment. The intervention consists of 8 weekly 30-min BA sessions delivered by a trained mental health nurse. Discussion: We expect BA to be an effective and cost-effective treatment for late-life depression compared to TAU. BA delivered by mental health nurses could increase the availability and accessibility of non-pharmacological treatments for late-life depression in primary care. Trial registration: This study is retrospectively registered in the Dutch Clinical Trial Register NTR6013on August 25th 2016.

LanguageEnglish
Article number230
JournalBMC Psychiatry
Volume17
Issue number1
DOIs
StatePublished - 26 Jun 2017

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Primary Health Care
Mental Health
Randomized Controlled Trials
Nurses
Depression
Therapeutics
Psychology
Psychotherapy
Health Care Costs
Netherlands
Suicide
Antidepressive Agents
Alcoholism
Multicenter Studies
Substance-Related Disorders
Cost-Benefit Analysis
Clinical Trials
Pharmacology
Costs and Cost Analysis

Keywords

  • Behavioural activation
  • Depressive symptoms
  • Late-life depression
  • Older adults
  • Primary care

Cite this

Janssen, N., Huibers, M. J. H., Lucassen, P. L. B. J., Voshaar, R. O., van Marwijk, H. W. J., Bosmans, J., ... Hendriks, G. J. (2017). Behavioural activation by mental health nurses for late-life depression in primary care: A randomized controlled trial. BMC Psychiatry, 17(1), [230]. DOI: 10.1186/s12888-017-1388-x
Janssen, Noortje ; Huibers, Marcus J.H. ; Lucassen, Peter L B J ; Voshaar, Richard Oude ; van Marwijk, Harm W J ; Bosmans, Judith ; Pijnappels, Mirjam ; Spijker, Jan ; Hendriks, Gert Jan. / Behavioural activation by mental health nurses for late-life depression in primary care : A randomized controlled trial. In: BMC Psychiatry. 2017 ; Vol. 17, No. 1.
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Behavioural activation by mental health nurses for late-life depression in primary care : A randomized controlled trial. / Janssen, Noortje; Huibers, Marcus J.H.; Lucassen, Peter L B J; Voshaar, Richard Oude; van Marwijk, Harm W J; Bosmans, Judith; Pijnappels, Mirjam; Spijker, Jan; Hendriks, Gert Jan.

In: BMC Psychiatry, Vol. 17, No. 1, 230, 26.06.2017.

Research output: Contribution to JournalArticleAcademicpeer-review

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