Biology and Genetics of Dizygotic and Monozygotic Twinning

J.J. Beck, Susanne Bruins, Hamdi Mbarek, Gareth Davies, Dorret Boomsma

Research output: Chapter in Book / Report / Conference proceedingChapterAcademic

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Abstract

This chapter summarizes what is known and what remains unknown about the human twinning process. The interest of this chapter is a description of the processes underlying twinning, with a specific focus on the biological and genetic aspects. While the mechanisms and contributory factors to dizygotic twinning are becoming well established, much remains unknown about the etiology of monozygotic twinning. Here we provide an overview of the incidence of twinning across the globe and present what is known about the influences of twinning based on the findings of historical, epidemiological, and more recent molecular studies.
Original languageEnglish
Title of host publicationTwin and Higher-order Pregnancies
EditorsA. Khalil, L. Lewi, E. Lopriore
PublisherSpringer Nature Switzerland AG
Pages31-50
Number of pages20
ISBN (Electronic)9783030476526
ISBN (Print)9783030476519
DOIs
Publication statusPublished - 2021

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