TY - JOUR
T1 - Biomonitoring of aquatic pollution with feral eel (Anguilla anguilla). II. Biomarkers: pollution-induced biochemical responses.
AU - van der Oost, R.
AU - Goksøyr, A.
AU - Celander, M.
AU - Heida, H.
AU - Vermeulen, N.P.E.
PY - 1996
Y1 - 1996
N2 - The primary aim of this study was to select a set of relevant biomarkers in feral eel for the biological assessment of inland water pollution. A suite of biochemical parameters in eel (hepatic biotransformation enzymes and cofactors, antioxidant enzymes, PAH metabolites, DNA adducts, serum transaminases) was measured in order to determine their response to xenobiotic compounds in the environment. The results of the analyses of organic trace pollutants in sediments and eel from six Amsterdam freshwater sites with different pollution levels have been discussed in the first part of this paper (Van der Oost, R., Opperhuizen, A., Satumalay, K., Heida, H. and Vermeulen, N.P.E., 1996a. Biomonitoring aquatic pollution with feral eel (Anguilla anguilla): I. Bioaccumulation: biota-sediment ratios of PCBs, OCPs, PCDDs and PCDFs. Aquat. Toxicol., 35: 21-46). The main conclusions drawn from the trends found for the levels and activities of biochemical parameters in eel were the following: the phase I biotransformation enzymes in eel liver appeared to be the most sensitive to environmental xenobiotics. Cytochrome b
AB - The primary aim of this study was to select a set of relevant biomarkers in feral eel for the biological assessment of inland water pollution. A suite of biochemical parameters in eel (hepatic biotransformation enzymes and cofactors, antioxidant enzymes, PAH metabolites, DNA adducts, serum transaminases) was measured in order to determine their response to xenobiotic compounds in the environment. The results of the analyses of organic trace pollutants in sediments and eel from six Amsterdam freshwater sites with different pollution levels have been discussed in the first part of this paper (Van der Oost, R., Opperhuizen, A., Satumalay, K., Heida, H. and Vermeulen, N.P.E., 1996a. Biomonitoring aquatic pollution with feral eel (Anguilla anguilla): I. Bioaccumulation: biota-sediment ratios of PCBs, OCPs, PCDDs and PCDFs. Aquat. Toxicol., 35: 21-46). The main conclusions drawn from the trends found for the levels and activities of biochemical parameters in eel were the following: the phase I biotransformation enzymes in eel liver appeared to be the most sensitive to environmental xenobiotics. Cytochrome b
U2 - 10.1016/S0166-445X(96)00802-8
DO - 10.1016/S0166-445X(96)00802-8
M3 - Article
SN - 0166-445X
VL - 36
SP - 189
EP - 222
JO - Aquatic Toxicology
JF - Aquatic Toxicology
ER -