Biotransformation of Endocrine Disrupting Compounds by Selected Phase I and Phase II Enzymes - Formation of Estrogenic and Chemically Reactive Metabolites by Cytochromes P450 and Sulfotransferases

Research output: Contribution to JournalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)500-527
JournalCurrent Medicinal Chemistry
Volume22
Issue number4
Publication statusPublished - 2015

Keywords

  • Bioactivation
  • biotransformation
  • Cytochromes P450 (CYPs)
  • endocrine disruption (ED)
  • endocrine disrupting compounds (EDCs)
  • estrogen receptor alpha (ER alpha)
  • reactive intermediates
  • sulfotransferases (SULTs)

Cite this

@article{f991903902504c7c9425f84c5f76c367,
title = "Biotransformation of Endocrine Disrupting Compounds by Selected Phase I and Phase II Enzymes - Formation of Estrogenic and Chemically Reactive Metabolites by Cytochromes P450 and Sulfotransferases",
keywords = "Bioactivation, biotransformation, Cytochromes P450 (CYPs), endocrine disruption (ED), endocrine disrupting compounds (EDCs), estrogen receptor alpha (ER alpha), reactive intermediates, sulfotransferases (SULTs)",
author = "J. Reinen and Vermeulen, {N. P. E.}",
year = "2015",
language = "English",
volume = "22",
pages = "500--527",
journal = "Current Medicinal Chemistry",
issn = "0929-8673",
publisher = "Bentham Science Publishers B.V.",
number = "4",

}

TY - JOUR

T1 - Biotransformation of Endocrine Disrupting Compounds by Selected Phase I and Phase II Enzymes - Formation of Estrogenic and Chemically Reactive Metabolites by Cytochromes P450 and Sulfotransferases

AU - Reinen, J.

AU - Vermeulen, N. P. E.

PY - 2015

Y1 - 2015

KW - Bioactivation

KW - biotransformation

KW - Cytochromes P450 (CYPs)

KW - endocrine disruption (ED)

KW - endocrine disrupting compounds (EDCs)

KW - estrogen receptor alpha (ER alpha)

KW - reactive intermediates

KW - sulfotransferases (SULTs)

M3 - Article

VL - 22

SP - 500

EP - 527

JO - Current Medicinal Chemistry

JF - Current Medicinal Chemistry

SN - 0929-8673

IS - 4

ER -