Bone tissue responses to zirconia implants modified by biomimetic coating incorporated with BMP-2

F. Teng; Y. Zheng; G. Wu; B. Beekmans; D. Wismeijer; Xingnan Lin; Y. Liu

doi:10.11607/prd.3980

Bone tissue responses to zirconia implants modified by biomimetic coating incorporated with BMP-2

F. Teng, Y. Zheng, G. Wu, B. Beekmans, D. Wismeijer, Xingnan Lin, Y. Liu

Reconstructive Oral Care

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

This study aimed to histologically investigate the bone tissue response to zirconia implants functionalized with a biomimetic calcium phosphate (CaP) coating incorporated with bone morphogenetic protein-2 (BMP-2). Zirconia implants coated with biomimetic CaP were prepared with and without BMP-2. Untreated zirconia implants served as a control. These three groups of implants were placed randomly in the mandibles of six beagle dogs (n = 6). Three months later, samples were harvested for histomorphometric analysis. The present study showed that the application of a biomimetic CaP coating incorporated with BMP-2 enhanced the peri-implant osteogenesis for zirconia implants.

Original language	English
Pages (from-to)	371-379
Number of pages	9
Journal	International Journal of Periodontics and Restorative Dentistry
Volume	39
Issue number	3
DOIs	https://doi.org/10.11607/prd.3980
Publication status	Published - May 2019

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abstract = "This study aimed to histologically investigate the bone tissue response to zirconia implants functionalized with a biomimetic calcium phosphate (CaP) coating incorporated with bone morphogenetic protein-2 (BMP-2). Zirconia implants coated with biomimetic CaP were prepared with and without BMP-2. Untreated zirconia implants served as a control. These three groups of implants were placed randomly in the mandibles of six beagle dogs (n = 6). Three months later, samples were harvested for histomorphometric analysis. The present study showed that the application of a biomimetic CaP coating incorporated with BMP-2 enhanced the peri-implant osteogenesis for zirconia implants.",

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AU - Wismeijer, D.

AU - Lin, Xingnan

AU - Liu, Y.

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AB - This study aimed to histologically investigate the bone tissue response to zirconia implants functionalized with a biomimetic calcium phosphate (CaP) coating incorporated with bone morphogenetic protein-2 (BMP-2). Zirconia implants coated with biomimetic CaP were prepared with and without BMP-2. Untreated zirconia implants served as a control. These three groups of implants were placed randomly in the mandibles of six beagle dogs (n = 6). Three months later, samples were harvested for histomorphometric analysis. The present study showed that the application of a biomimetic CaP coating incorporated with BMP-2 enhanced the peri-implant osteogenesis for zirconia implants.

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Bone tissue responses to zirconia implants modified by biomimetic coating incorporated with BMP-2

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