Brain regions activated by endogenous preparatory set shifting as revealed by fMRI

H. A. Slagter, D. H. Weissman, B. Giesbrecht, J. L. Kenemans, G. R. Mangun, A. Kok, M. G. Woldorff*

*Corresponding author for this work

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

An ongoing controversy concerns whether executive control mechanisms can actively reconfigure the cognitive system in preparation for switching to a new task set. To address this question, we recorded brain activity from 14 healthy participants, using event-related functional magnetic resonance imaging, while they performed a cued attention task. Critically, in any particular trial, the cued task set was either the same as that in the previous trial or switched. As was hypothesized, cue-related, switch-specific preparatory activity was observed in a network of dorsal frontal and parietal brain areas that are typically associated with cognitive control processes. Moreover, the magnitude of switch-specific preparatory activity varied with the number of possible task sets that could be presented in a given trial block. These findings provide compelling support for the existence of top-down, preparatory control processes that enable set switching. Furthermore, they demonstrate that global task structure is a critical determinant of whether switch-specific preparatory activity is observed.

Original languageEnglish
Pages (from-to)175-189
Number of pages15
JournalCognitive, Affective and Behavioral Neuroscience
Volume6
Issue number3
DOIs
Publication statusPublished - 1 Sep 2006
Externally publishedYes

Fingerprint

Dive into the research topics of 'Brain regions activated by endogenous preparatory set shifting as revealed by fMRI'. Together they form a unique fingerprint.

Cite this