TY - JOUR
T1 - Breakpoint identification and smoothing of array comparative genomic hybridization data
AU - Jong, C.
AU - Marchiori, E.
AU - Meijer, G.J.
AU - van der Vaart, A.W.
AU - Ylstra, B.
PY - 2004
Y1 - 2004
N2 - Summary: We describe a tool, called aCGH-Smooth, for the automated identification of breakpoints and smoothing of microarray comparative genomic hybridization (array CGH) data. aCGH-Smooth is written in visual C++, has a user-friendly interface including a visualization of the results and user-defined parameters adapting the performance of data smoothing and breakpoint recognition. aCGH-Smooth can handle array-CGH data generated by all array-CGH platforms: BAC, PAC, cosmid, cDNA and oligo CGH arrays. The tool has been successfully applied to real-life data. © Oxford University Press 2004; all rights reserved.
AB - Summary: We describe a tool, called aCGH-Smooth, for the automated identification of breakpoints and smoothing of microarray comparative genomic hybridization (array CGH) data. aCGH-Smooth is written in visual C++, has a user-friendly interface including a visualization of the results and user-defined parameters adapting the performance of data smoothing and breakpoint recognition. aCGH-Smooth can handle array-CGH data generated by all array-CGH platforms: BAC, PAC, cosmid, cDNA and oligo CGH arrays. The tool has been successfully applied to real-life data. © Oxford University Press 2004; all rights reserved.
U2 - 10.1093/bioinformatics/bth355
DO - 10.1093/bioinformatics/bth355
M3 - Article
SN - 1367-4803
VL - 20
SP - 3636
EP - 3637
JO - Bioinformatics (Oxford, England)
JF - Bioinformatics (Oxford, England)
IS - 18
ER -
