BRET-based beta-arrestin2 recruitmanet to the histamine H1 receptor for investigating antihistamine binding kinetics.

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

Ligand residence time is thought to be a critical parameter for optimizing the in vivo efficacy of drug candidates. For the histamine H
Original languageEnglish
Pages (from-to)679-687
JournalPharmacological Research
Issue number111
DOIs
Publication statusPublished - 2016

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Histamine H1 Receptors
Histamine Antagonists
Histamine
Ligands
Pharmaceutical Preparations

Cite this

@article{6948ea25f69d465b9c1c2655bd577020,
title = "BRET-based beta-arrestin2 recruitmanet to the histamine H1 receptor for investigating antihistamine binding kinetics.",
abstract = "Ligand residence time is thought to be a critical parameter for optimizing the in vivo efficacy of drug candidates. For the histamine H",
author = "R. Bosma and R. Moritani and R. Leurs and H.F. Vischer",
year = "2016",
doi = "10.1016/j.phrs.2016.07.034",
language = "English",
pages = "679--687",
journal = "Pharmacological Research",
issn = "1043-6618",
publisher = "Academic Press Inc.",
number = "111",

}

BRET-based beta-arrestin2 recruitmanet to the histamine H1 receptor for investigating antihistamine binding kinetics. / Bosma, R.; Moritani, R.; Leurs, R.; Vischer, H.F.

In: Pharmacological Research, No. 111, 2016, p. 679-687.

Research output: Contribution to JournalArticleAcademicpeer-review

TY - JOUR

T1 - BRET-based beta-arrestin2 recruitmanet to the histamine H1 receptor for investigating antihistamine binding kinetics.

AU - Bosma, R.

AU - Moritani, R.

AU - Leurs, R.

AU - Vischer, H.F.

PY - 2016

Y1 - 2016

N2 - Ligand residence time is thought to be a critical parameter for optimizing the in vivo efficacy of drug candidates. For the histamine H

AB - Ligand residence time is thought to be a critical parameter for optimizing the in vivo efficacy of drug candidates. For the histamine H

U2 - 10.1016/j.phrs.2016.07.034

DO - 10.1016/j.phrs.2016.07.034

M3 - Article

SP - 679

EP - 687

JO - Pharmacological Research

JF - Pharmacological Research

SN - 1043-6618

IS - 111

ER -