Broadband dynamics rather than frequency-specific rhythms underlie prediction error in the primate auditory cortex

Andrés Canales-Johnson*, Ana Filipa Teixeira Borges, Misako Komatsu, Naotaka Fujii, Johannes J. Fahrenfort, Kai J. Miller, Valdas Noreika

*Corresponding author for this work

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

Detection of statistical irregularities, measured as a prediction error response, is fundamental to the perceptual monitoring of the environment. We studied whether prediction error response is associated with neural oscillations or asynchronous broadband activity. Electrocorticography was conducted in three male monkeys, who passively listened to the auditory roving oddball stimuli. Local field potentials (LFPs) recorded over the auditory cortex underwent spectral principal component analysis, which decoupled broadband and rhythmic components of the LFP signal. We found that the broadband component captured the prediction error response, whereas none of the rhythmic components were associated with statistical irregularities of sounds. The broadband component displayed more stochastic, asymmetrical multifractal properties than the rhythmic components, which revealed more self-similar dynamics. We thus conclude that the prediction error response is captured by neuronal populations generating asynchronous broadband activity, defined by irregular dynamic states, which, unlike oscillatory rhythms, appear to enable the neural representation of auditory prediction error response.

Original languageEnglish
Pages (from-to)9374-9391
Number of pages18
JournalJournal of Neuroscience
Volume41
Issue number45
DOIs
Publication statusPublished - 10 Nov 2021

Bibliographical note

Publisher Copyright:
Copyright © 2021 the authors

Keywords

  • Auditory cortex
  • Broadband response
  • Mismatch negativity
  • Multiscale multifractal analysis
  • Prediction error
  • Rhythmic components

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