Cardiorespiratory Fitness in Individuals Post-stroke: Reference Values and Determinants

Ilse J. Blokland; Floor P. Groot; Nadine H.G. Logt; Coen A.M. van Bennekom; Jos J. de Koning; Jaap H. van Dieen; Han Houdijk

doi:10.1016/j.apmr.2023.03.035

Cardiorespiratory Fitness in Individuals Post-stroke: Reference Values and Determinants

Ilse J. Blokland, Floor P. Groot, Nadine H.G. Logt, Coen A.M. van Bennekom, Jos J. de Koning, Jaap H. van Dieen, Han Houdijk

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

Objective: To provide reference values of cardiorespiratory fitness for individuals post-stroke in clinical rehabilitation and to gain insight in characteristics related to cardiorespiratory fitness post stroke. Design: A retrospective cohort study. Reference equations of cardiopulmonary fitness corrected for age and sex for the fifth, 25th, 50th, 75th, and 95th percentile were constructed with quantile regression analysis. The relation between patient characteristics and cardiorespiratory fitness was determined by linear regression analyses adjusted for sex and age. Multivariate regression models of cardiorespiratory fitness were constructed. Setting: Clinical rehabilitation center. Participants: Individuals post-stroke who performed a cardiopulmonary exercise test as part of clinical rehabilitation between July 2015 and May 2021 (N=405). Main Outcome Measures: Cardiorespiratory fitness in terms of peak oxygen uptake (V˙O2peak) and oxygen uptake at ventilatory threshold (V˙O2-VT). Results: References equations for cardiorespiratory fitness stratified by sex and age were provided based on 405 individuals post-stroke. Median V˙O2peak was 17.8[range 8.4-39.6] mL/kg/min and median V˙O2-VT was 9.7[range 5.9-26.6] mL/kg/min. Cardiorespiratory fitness was lower in individuals who were older, women, using beta-blocker medication, and in individuals with a higher body mass index and lower motor ability. Conclusions: Population specific reference values of cardiorespiratory fitness for individuals post-stroke corrected for age and sex were presented. These can give individuals post-stroke and health care providers insight in their cardiorespiratory fitness compared with their peers. Furthermore, they can be used to determine the potential necessity for cardiorespiratory fitness training as part of the rehabilitation program for an individual post-stroke to enhance their fitness, functioning and health. Especially, individuals post-stroke with more mobility limitations and beta-blocker use are at a higher risk of low cardiorespiratory fitness.

Original language	English
Pages (from-to)	1612-1619
Journal	Archives of Physical Medicine and Rehabilitation
Volume	104
Issue number	10
DOIs	https://doi.org/10.1016/j.apmr.2023.03.035
Publication status	Published - 1 Oct 2023

Funding

We would like to thank all participants who allowed us to use their data, and the teams from Heliomare and Sport- en BeweegKliniek Haarlem that performed the CPETS. Special thanks to Bas Vader, Richard Fickert, Kees de Kok, Claudia Hilbers, Shanna Illbrink, Feikje Riedstra, and Jan-Willem Dijkstra.

Funders	Funder number
CPETS
Heliomare and Sport- en BeweegKliniek Haarlem

Access to Document

10.1016/j.apmr.2023.03.035

Persistent URL (handle)

Copy link address

Cite this

@article{ea2699f6d0064603b82d65c5533ad30e,

title = "Cardiorespiratory Fitness in Individuals Post-stroke: Reference Values and Determinants",

abstract = "Objective: To provide reference values of cardiorespiratory fitness for individuals post-stroke in clinical rehabilitation and to gain insight in characteristics related to cardiorespiratory fitness post stroke. Design: A retrospective cohort study. Reference equations of cardiopulmonary fitness corrected for age and sex for the fifth, 25th, 50th, 75th, and 95th percentile were constructed with quantile regression analysis. The relation between patient characteristics and cardiorespiratory fitness was determined by linear regression analyses adjusted for sex and age. Multivariate regression models of cardiorespiratory fitness were constructed. Setting: Clinical rehabilitation center. Participants: Individuals post-stroke who performed a cardiopulmonary exercise test as part of clinical rehabilitation between July 2015 and May 2021 (N=405). Main Outcome Measures: Cardiorespiratory fitness in terms of peak oxygen uptake (V˙O2peak) and oxygen uptake at ventilatory threshold (V˙O2-VT). Results: References equations for cardiorespiratory fitness stratified by sex and age were provided based on 405 individuals post-stroke. Median V˙O2peak was 17.8[range 8.4-39.6] mL/kg/min and median V˙O2-VT was 9.7[range 5.9-26.6] mL/kg/min. Cardiorespiratory fitness was lower in individuals who were older, women, using beta-blocker medication, and in individuals with a higher body mass index and lower motor ability. Conclusions: Population specific reference values of cardiorespiratory fitness for individuals post-stroke corrected for age and sex were presented. These can give individuals post-stroke and health care providers insight in their cardiorespiratory fitness compared with their peers. Furthermore, they can be used to determine the potential necessity for cardiorespiratory fitness training as part of the rehabilitation program for an individual post-stroke to enhance their fitness, functioning and health. Especially, individuals post-stroke with more mobility limitations and beta-blocker use are at a higher risk of low cardiorespiratory fitness.",

author = "Blokland, {Ilse J.} and Groot, {Floor P.} and Logt, {Nadine H.G.} and {van Bennekom}, {Coen A.M.} and {de Koning}, {Jos J.} and {van Dieen}, {Jaap H.} and Han Houdijk",

year = "2023",

month = oct,

day = "1",

doi = "10.1016/j.apmr.2023.03.035",

language = "English",

volume = "104",

pages = "1612--1619",

journal = "Archives of Physical Medicine and Rehabilitation",

issn = "0003-9993",

publisher = "W.B. Saunders Ltd",

number = "10",

}

TY - JOUR

T1 - Cardiorespiratory Fitness in Individuals Post-stroke

T2 - Reference Values and Determinants

AU - Blokland, Ilse J.

AU - Groot, Floor P.

AU - Logt, Nadine H.G.

AU - van Bennekom, Coen A.M.

AU - de Koning, Jos J.

AU - van Dieen, Jaap H.

AU - Houdijk, Han

PY - 2023/10/1

Y1 - 2023/10/1

N2 - Objective: To provide reference values of cardiorespiratory fitness for individuals post-stroke in clinical rehabilitation and to gain insight in characteristics related to cardiorespiratory fitness post stroke. Design: A retrospective cohort study. Reference equations of cardiopulmonary fitness corrected for age and sex for the fifth, 25th, 50th, 75th, and 95th percentile were constructed with quantile regression analysis. The relation between patient characteristics and cardiorespiratory fitness was determined by linear regression analyses adjusted for sex and age. Multivariate regression models of cardiorespiratory fitness were constructed. Setting: Clinical rehabilitation center. Participants: Individuals post-stroke who performed a cardiopulmonary exercise test as part of clinical rehabilitation between July 2015 and May 2021 (N=405). Main Outcome Measures: Cardiorespiratory fitness in terms of peak oxygen uptake (V˙O2peak) and oxygen uptake at ventilatory threshold (V˙O2-VT). Results: References equations for cardiorespiratory fitness stratified by sex and age were provided based on 405 individuals post-stroke. Median V˙O2peak was 17.8[range 8.4-39.6] mL/kg/min and median V˙O2-VT was 9.7[range 5.9-26.6] mL/kg/min. Cardiorespiratory fitness was lower in individuals who were older, women, using beta-blocker medication, and in individuals with a higher body mass index and lower motor ability. Conclusions: Population specific reference values of cardiorespiratory fitness for individuals post-stroke corrected for age and sex were presented. These can give individuals post-stroke and health care providers insight in their cardiorespiratory fitness compared with their peers. Furthermore, they can be used to determine the potential necessity for cardiorespiratory fitness training as part of the rehabilitation program for an individual post-stroke to enhance their fitness, functioning and health. Especially, individuals post-stroke with more mobility limitations and beta-blocker use are at a higher risk of low cardiorespiratory fitness.

AB - Objective: To provide reference values of cardiorespiratory fitness for individuals post-stroke in clinical rehabilitation and to gain insight in characteristics related to cardiorespiratory fitness post stroke. Design: A retrospective cohort study. Reference equations of cardiopulmonary fitness corrected for age and sex for the fifth, 25th, 50th, 75th, and 95th percentile were constructed with quantile regression analysis. The relation between patient characteristics and cardiorespiratory fitness was determined by linear regression analyses adjusted for sex and age. Multivariate regression models of cardiorespiratory fitness were constructed. Setting: Clinical rehabilitation center. Participants: Individuals post-stroke who performed a cardiopulmonary exercise test as part of clinical rehabilitation between July 2015 and May 2021 (N=405). Main Outcome Measures: Cardiorespiratory fitness in terms of peak oxygen uptake (V˙O2peak) and oxygen uptake at ventilatory threshold (V˙O2-VT). Results: References equations for cardiorespiratory fitness stratified by sex and age were provided based on 405 individuals post-stroke. Median V˙O2peak was 17.8[range 8.4-39.6] mL/kg/min and median V˙O2-VT was 9.7[range 5.9-26.6] mL/kg/min. Cardiorespiratory fitness was lower in individuals who were older, women, using beta-blocker medication, and in individuals with a higher body mass index and lower motor ability. Conclusions: Population specific reference values of cardiorespiratory fitness for individuals post-stroke corrected for age and sex were presented. These can give individuals post-stroke and health care providers insight in their cardiorespiratory fitness compared with their peers. Furthermore, they can be used to determine the potential necessity for cardiorespiratory fitness training as part of the rehabilitation program for an individual post-stroke to enhance their fitness, functioning and health. Especially, individuals post-stroke with more mobility limitations and beta-blocker use are at a higher risk of low cardiorespiratory fitness.

UR - http://www.scopus.com/inward/record.url?scp=85163412854&partnerID=8YFLogxK

U2 - 10.1016/j.apmr.2023.03.035

DO - 10.1016/j.apmr.2023.03.035

M3 - Article

SN - 0003-9993

VL - 104

SP - 1612

EP - 1619

JO - Archives of Physical Medicine and Rehabilitation

JF - Archives of Physical Medicine and Rehabilitation

IS - 10

ER -

Cardiorespiratory Fitness in Individuals Post-stroke: Reference Values and Determinants

Abstract

Funding

Access to Document

Persistent URL (handle)

Other files and links

Fingerprint

Cite this