CGHnormaliter: a bioconductor package for normalization of array CGH data with many CNAs.

B.P.P. van Houte; T.W. Binsl; H. Hettling; J. Heringa

doi:10.1093/bioinformatics/btq155

CGHnormaliter: a bioconductor package for normalization of array CGH data with many CNAs.

B.P.P. van Houte, T.W. Binsl, H. Hettling, J. Heringa

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

Summary: CGHnormaliter is a package for normalization of array comparative genomic hybridization (aCGH) data. It uses an iterative procedure that effectively eliminates the influence of imbalanced copy numbers. This leads to a more reliable assessment of copy number alterations (CNAs). CGHnormaliter is integrated in the Bioconductor environment allowing a smooth link to visualization tools and further data analysis. Availability and Implementation: The CGHnormaliter package is implemented in R and under GPL 3.0 license available at Bioconductor: http://www.bioconductor.org. Contact: [email protected]. © The Author 2010. Published by Oxford University Press. All rights reserved. For Permissions, please email: [email protected].

Original language	English
Pages (from-to)	1366-1367
Journal	Bioinformatics
Volume	26
DOIs	https://doi.org/10.1093/bioinformatics/btq155
Publication status	Published - 2010

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title = "CGHnormaliter: a bioconductor package for normalization of array CGH data with many CNAs.",

abstract = "Summary: CGHnormaliter is a package for normalization of array comparative genomic hybridization (aCGH) data. It uses an iterative procedure that effectively eliminates the influence of imbalanced copy numbers. This leads to a more reliable assessment of copy number alterations (CNAs). CGHnormaliter is integrated in the Bioconductor environment allowing a smooth link to visualization tools and further data analysis. Availability and Implementation: The CGHnormaliter package is implemented in R and under GPL 3.0 license available at Bioconductor: http://www.bioconductor.org. Contact: [email protected]. {\textcopyright} The Author 2010. Published by Oxford University Press. All rights reserved. For Permissions, please email: [email protected].",

author = "{van Houte}, B.P.P. and T.W. Binsl and H. Hettling and J. Heringa",

year = "2010",

doi = "10.1093/bioinformatics/btq155",

language = "English",

volume = "26",

pages = "1366--1367",

journal = "Bioinformatics",

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T1 - CGHnormaliter: a bioconductor package for normalization of array CGH data with many CNAs.

AU - van Houte, B.P.P.

AU - Binsl, T.W.

AU - Hettling, H.

AU - Heringa, J.

PY - 2010

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N2 - Summary: CGHnormaliter is a package for normalization of array comparative genomic hybridization (aCGH) data. It uses an iterative procedure that effectively eliminates the influence of imbalanced copy numbers. This leads to a more reliable assessment of copy number alterations (CNAs). CGHnormaliter is integrated in the Bioconductor environment allowing a smooth link to visualization tools and further data analysis. Availability and Implementation: The CGHnormaliter package is implemented in R and under GPL 3.0 license available at Bioconductor: http://www.bioconductor.org. Contact: [email protected]. © The Author 2010. Published by Oxford University Press. All rights reserved. For Permissions, please email: [email protected].

AB - Summary: CGHnormaliter is a package for normalization of array comparative genomic hybridization (aCGH) data. It uses an iterative procedure that effectively eliminates the influence of imbalanced copy numbers. This leads to a more reliable assessment of copy number alterations (CNAs). CGHnormaliter is integrated in the Bioconductor environment allowing a smooth link to visualization tools and further data analysis. Availability and Implementation: The CGHnormaliter package is implemented in R and under GPL 3.0 license available at Bioconductor: http://www.bioconductor.org. Contact: [email protected]. © The Author 2010. Published by Oxford University Press. All rights reserved. For Permissions, please email: [email protected].

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DO - 10.1093/bioinformatics/btq155

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VL - 26

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JO - Bioinformatics

JF - Bioinformatics

ER -

CGHnormaliter: a bioconductor package for normalization of array CGH data with many CNAs.

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