CGHnormaliter: a bioconductor package for normalization of array CGH data with many CNAs.

B.P.P. van Houte, T.W. Binsl, H. Hettling, J. Heringa

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

Summary: CGHnormaliter is a package for normalization of array comparative genomic hybridization (aCGH) data. It uses an iterative procedure that effectively eliminates the influence of imbalanced copy numbers. This leads to a more reliable assessment of copy number alterations (CNAs). CGHnormaliter is integrated in the Bioconductor environment allowing a smooth link to visualization tools and further data analysis. Availability and Implementation: The CGHnormaliter package is implemented in R and under GPL 3.0 license available at Bioconductor: http://www.bioconductor.org. Contact: heringa@few.vu.nl. © The Author 2010. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org.
Original languageEnglish
Pages (from-to)1366-1367
JournalBioinformatics
Volume26
DOIs
Publication statusPublished - 2010

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