TY - JOUR
T1 - Challenges and solutions in prognostic prediction models in spinal disorders
AU - Wingbermuhle, Roel
AU - Chiarotto, Alessandro
AU - Koes, Bart
AU - Heymans, Martijn W
AU - van Trijffel, Emiel
N1 - Copyright © 2020 Elsevier Inc. All rights reserved.
PY - 2021/4
Y1 - 2021/4
N2 - Methodological shortcomings in prognostic modeling for patients with spinal disorders are highly common. This general commentary discusses methodological challenges related to the specific nature of this field. Five specific methodological challenges in prognostic modeling for patients with spinal disorders are presented with their potential solutions, as related to the choice of study participants, purpose of studies, limitations in measurements of outcomes and predictors, complexity of recovery predictions, and confusion of prognosis and treatment response. Large studies specifically designed for prognostic model research are needed, using standard baseline measurement sets, clearly describing participants’ recruitment and accounting and correcting for measurement limitations.
AB - Methodological shortcomings in prognostic modeling for patients with spinal disorders are highly common. This general commentary discusses methodological challenges related to the specific nature of this field. Five specific methodological challenges in prognostic modeling for patients with spinal disorders are presented with their potential solutions, as related to the choice of study participants, purpose of studies, limitations in measurements of outcomes and predictors, complexity of recovery predictions, and confusion of prognosis and treatment response. Large studies specifically designed for prognostic model research are needed, using standard baseline measurement sets, clearly describing participants’ recruitment and accounting and correcting for measurement limitations.
U2 - 10.1016/j.jclinepi.2020.12.017
DO - 10.1016/j.jclinepi.2020.12.017
M3 - Article
C2 - 33359321
SN - 0895-4356
VL - 132
SP - 125
EP - 130
JO - Journal of Clinical Epidemiology
JF - Journal of Clinical Epidemiology
ER -