Changes in gait characteristics of women with early and established medial knee osteoarthritis: Results from a 2-years longitudinal study

Armaghan Mahmoudian, Jaap H. van Dieёn, Isabel A.C. Baert, Sjoerd M. Bruijn, Gert S. Faber, Frank P. Luyten, Sabine M.P. Verschueren*

*Corresponding author for this work

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

Background Despite the large number of cross-sectional studies on gait in subjects with knee osteoarthritis, there are scarcely any longitudinal studies on gait changes in knee osteoarthritis. Methods Gait analysis was performed on 25 women with early and 18 with established medial knee osteoarthritis, as well as a group of 23 healthy controls. Subjects were asked to walk at their comfortable speed. Kinematic and kinetic data were measured at baseline and after 2 years follow-up. Findings Results indicated that the early osteoarthritis group, similar to established osteoarthritis group, showed significantly higher maximum knee adduction angles compared to the controls during the early stance phase of gait. None of the kinematic or kinetic measures, changed over two years in the early osteoarthritis group. In the established osteoarthritis group, at the time of entry, an increased first and second peak knee adduction moment, as well as higher mid-stance knee adduction moment and knee adduction moment impulse, were present compared to the control and the early osteoarthritis groups. Mid-stance knee adduction moment and knee adduction moment impulse, further increased over two years only in the established osteoarthritis group. For all three groups, the peak knee flexion angle during the stance phase decreased significantly over time. Interpretation Increased maximum knee adduction angle during stance phase was the only alteration in the gait pattern of subjects with early knee osteoarthritis compared to the controls. This suggests that, unlike in the later stages of the disease, gait is rather stable over two years in early osteoarthritis.

Original languageEnglish
Pages (from-to)32-39
Number of pages8
JournalClinical Biomechanics
Volume50
DOIs
Publication statusPublished - 1 Dec 2017

Keywords

  • Gait analysis
  • Knee
  • Knee adduction moment
  • OA severity

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