Changes in immunological profile as a function of urbanization and life style.

M. Mbow, S.E. de Jong, L. Meurs, S. Mboup, T.N. Dieye, K. Polman, M. Yazdanbakhsh

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

Summary: Differences in lifestyle and break with natural environment appear to be associated with changes in the immune system resulting in various adverse health effects. Although genetics can have a major impact on the immune system and disease susceptibility, the contribution of environmental factors is thought to be substantial. Here, we investigated the immunological profile of healthy volunteers living in a rural and an urban area of a developing African country (Senegal), and in a European country (the Netherlands). Using flow cytometry, we investigated T helper type 1 (Th1), Th2, Th17, Th22 and regulatory T cells, as well as CD4
Original languageEnglish
JournalImmunology
Volume2014
Issue number12
DOIs
Publication statusPublished - 2014

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