Chemical and glutathione conjugation-related degradation of fotemustine: formation and characterization of a glutathione conjugate of diethyl (1-isocyanatoethyl)phosphonate, a reactive metabolite of fotemustine.

J.P. Brakenhoff; J.N.M. Commandeur; F.J.J. de Kanter; B.L. Baar; W.C. Luijten; N.P.E. Vermeulen

doi:10.1021/tx00039a016

Chemical and glutathione conjugation-related degradation of fotemustine: formation and characterization of a glutathione conjugate of diethyl (1-isocyanatoethyl)phosphonate, a reactive metabolite of fotemustine.

J.P. Brakenhoff, J.N.M. Commandeur, F.J.J. de Kanter, B.L. Baar, W.C. Luijten, N.P.E. Vermeulen

Research output: Contribution to Journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	380-389
Journal	Chemical Research in Toxicology
Volume	7
Issue number	3
DOIs	https://doi.org/10.1021/tx00039a016
Publication status	Published - 1994

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10.1021/tx00039a016

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Brakenhoff, J. P., Commandeur, J. N. M., de Kanter, F. J. J., Baar, B. L., Luijten, W. C., & Vermeulen, N. P. E. (1994). Chemical and glutathione conjugation-related degradation of fotemustine: formation and characterization of a glutathione conjugate of diethyl (1-isocyanatoethyl)phosphonate, a reactive metabolite of fotemustine. Chemical Research in Toxicology, 7(3), 380-389. https://doi.org/10.1021/tx00039a016

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title = "Chemical and glutathione conjugation-related degradation of fotemustine: formation and characterization of a glutathione conjugate of diethyl (1-isocyanatoethyl)phosphonate, a reactive metabolite of fotemustine.",

author = "J.P. Brakenhoff and J.N.M. Commandeur and {de Kanter}, F.J.J. and B.L. Baar and W.C. Luijten and N.P.E. Vermeulen",

year = "1994",

doi = "10.1021/tx00039a016",

language = "English",

volume = "7",

pages = "380--389",

journal = "Chemical Research in Toxicology",

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Brakenhoff, JP, Commandeur, JNM, de Kanter, FJJ, Baar, BL, Luijten, WC & Vermeulen, NPE 1994, 'Chemical and glutathione conjugation-related degradation of fotemustine: formation and characterization of a glutathione conjugate of diethyl (1-isocyanatoethyl)phosphonate, a reactive metabolite of fotemustine.', Chemical Research in Toxicology, vol. 7, no. 3, pp. 380-389. https://doi.org/10.1021/tx00039a016

Chemical and glutathione conjugation-related degradation of fotemustine: formation and characterization of a glutathione conjugate of diethyl (1-isocyanatoethyl)phosphonate, a reactive metabolite of fotemustine. / Brakenhoff, J.P.; Commandeur, J.N.M.; de Kanter, F.J.J. et al.
In: Chemical Research in Toxicology, Vol. 7, No. 3, 1994, p. 380-389.

Research output: Contribution to Journal › Article › Academic › peer-review

TY - JOUR

T1 - Chemical and glutathione conjugation-related degradation of fotemustine: formation and characterization of a glutathione conjugate of diethyl (1-isocyanatoethyl)phosphonate, a reactive metabolite of fotemustine.

AU - Brakenhoff, J.P.

AU - Commandeur, J.N.M.

AU - de Kanter, F.J.J.

AU - Baar, B.L.

AU - Luijten, W.C.

AU - Vermeulen, N.P.E.

PY - 1994

Y1 - 1994

U2 - 10.1021/tx00039a016

DO - 10.1021/tx00039a016

M3 - Article

SN - 0893-228X

VL - 7

SP - 380

EP - 389

JO - Chemical Research in Toxicology

JF - Chemical Research in Toxicology

IS - 3

ER -

Brakenhoff JP, Commandeur JNM, de Kanter FJJ, Baar BL, Luijten WC, Vermeulen NPE. Chemical and glutathione conjugation-related degradation of fotemustine: formation and characterization of a glutathione conjugate of diethyl (1-isocyanatoethyl)phosphonate, a reactive metabolite of fotemustine. Chemical Research in Toxicology. 1994;7(3):380-389. doi: 10.1021/tx00039a016