Chromatin accessibility during human first-trimester neurodevelopment

Funding

We thank the women who have decided to donate to science, making this study possible; the Developmental Tissue Bank (Department of Neurobiology, Care Sciences and Society, Karolinska Institutet) core facility, the Human Developmental Biology Resource (UK) and Cambridge University for providing prenatal tissue samples; Y.\u2009E.\u2009Li and B.\u2009Ren for hosting the online dataset; J.\u2009B.\u2009Munting for providing supplementary code used while training the CNN; E.\u2009Vinsland for assistance collecting samples; I.\u2009Kapustova for providing illustrations; and all members of the Linnarsson laboratory and M.\u2009Bartosovic, M.\u2009Kabbe and J.\u2009Hjerling-Leffler for discussions. This research was supported by the National Institute for Health and Care Research Cambridge Biomedical Research Centre (BRC-1215-20014). The views expressed are those of the authors and not necessarily those of the National Institute for Health and Care Research or the Department of Health and Social Care. This work is financed by the following grants: an Erling-Persson Foundation Human Developmental Cell Atlas grant (S.L.), Knut and Alice Wallenberg Foundation grants 2015.0041, 2018.0172 and 2018.0220 (S.L.), Swedish Foundation for Strategic Research SB16-0065 (S.L.) and EU Horizon2020 BRAINTIME project 874606 (S.L.). We also acknowledge support from the National Genomics Infrastructure in Stockholm financed by the Science for Life Laboratory, the Knut and Alice Wallenberg Foundation and the Swedish Research Council. For the purpose of open access, the author has applied a Creative Commons Attribution (CC BY) licence to any author accepted manuscript version arising from this submission.