Classification and treatment follow-up of a juxtapapillary retinal hemangioblastoma with optical coherence tomography angiography

Lisette M. Smid, Koen A. van Overdam, Valentina Davidoiu, Jan H. de Jong, Johannes F. de Boer, Koenraad A. Vermeer, Mirjam E.J. van Velthoven

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

Purpose: Only an endophytic growth pattern in juxtapapillary retinal hemangioblastoma (JRH) is an indication for surgical treatment, but classification of growth types is difficult using conventional imaging techniques. This case report describes the use of optical coherence tomography angiography (OCT-A) features for classification and treatment follow-up in a case with JRH. Observations: The JRH of this patient was easily detected with two different OCT-A methods in both en-face and cross-sectional B-scan images, and was classified as a sessile growth type. This growth type excluded the treatment option of vitreoretinal surgery with excision of the lesion or ligation of the feeder vessels. The patient was treated multiple times with intravitreal bevacizumab. Treatment follow-up with OCT-A initially revealed a stable extent of the JRH, with some slight flow deviations in en-face visualization, followed by a period of progressive growth of the lesion. Conclusions: OCT-A revealed the depth localization of the JRH and seems to be a valuable tool for JRH classification. Detailed classification may be useful when surgery is considered as a treatment strategy. Furthermore, treatment follow-up is possible with OCT-A, although imaging artifacts should be taken into account.

Original languageEnglish
Article number100472
JournalAmerican Journal of Ophthalmology Case Reports
Volume15
DOIs
Publication statusPublished - 1 Sep 2019

Fingerprint

Hemangioblastoma
Optical Coherence Tomography
Angiography
Growth
Therapeutics
Vitreoretinal Surgery
Artifacts
Ligation

Keywords

  • Doppler OCT
  • Intravitreal bevacizumab
  • Juxtapapillary retinal hemangioblastoma
  • Optical coherence tomography angiography
  • Sessile

Cite this

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title = "Classification and treatment follow-up of a juxtapapillary retinal hemangioblastoma with optical coherence tomography angiography",
abstract = "Purpose: Only an endophytic growth pattern in juxtapapillary retinal hemangioblastoma (JRH) is an indication for surgical treatment, but classification of growth types is difficult using conventional imaging techniques. This case report describes the use of optical coherence tomography angiography (OCT-A) features for classification and treatment follow-up in a case with JRH. Observations: The JRH of this patient was easily detected with two different OCT-A methods in both en-face and cross-sectional B-scan images, and was classified as a sessile growth type. This growth type excluded the treatment option of vitreoretinal surgery with excision of the lesion or ligation of the feeder vessels. The patient was treated multiple times with intravitreal bevacizumab. Treatment follow-up with OCT-A initially revealed a stable extent of the JRH, with some slight flow deviations in en-face visualization, followed by a period of progressive growth of the lesion. Conclusions: OCT-A revealed the depth localization of the JRH and seems to be a valuable tool for JRH classification. Detailed classification may be useful when surgery is considered as a treatment strategy. Furthermore, treatment follow-up is possible with OCT-A, although imaging artifacts should be taken into account.",
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Classification and treatment follow-up of a juxtapapillary retinal hemangioblastoma with optical coherence tomography angiography. / Smid, Lisette M.; van Overdam, Koen A.; Davidoiu, Valentina; de Jong, Jan H.; de Boer, Johannes F.; Vermeer, Koenraad A.; van Velthoven, Mirjam E.J.

In: American Journal of Ophthalmology Case Reports, Vol. 15, 100472, 01.09.2019.

Research output: Contribution to JournalArticleAcademicpeer-review

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AU - de Boer, Johannes F.

AU - Vermeer, Koenraad A.

AU - van Velthoven, Mirjam E.J.

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