Abstract
Significant treatment variation exists in the Netherlands between teams treating patients with cleft lip, alveolus, and/or palate, resulting in a confusing and undesirable situation for patients, parents, and practitioners. Therefore, to optimize cleft care, clinical practice guidelines (CPGs) were developed. The aim of this report is to describe CPG development, share the main recommendations, and indicate knowledge gaps regarding cleft care. Together with patients and parents, a multidisciplinary working group of representatives from all relevant disciplines assisted by two experienced epidemiologists identified the topics to be addressed in the CPGs. Searching the Medline, Embase, and Cochrane Library databases identified 5157 articles, 60 of which remained after applying inclusion and exclusion criteria. We rated the quality of the evidence from moderate to very low. The working group formulated 71 recommendations regarding genetic testing, feeding, lip and palate closure, hearing, hypernasality, bone grafting, orthodontics, psychosocial guidance, dentistry, osteotomy versus distraction, and rhinoplasty. The final CPGs were obtained after review by all stakeholders and allow cleft teams to base their treatment on current knowledge. With high-quality evidence lacking, the need for additional high‐quality studies has become apparent.
Original language | English |
---|---|
Article number | 4813 |
Pages (from-to) | 1-14 |
Number of pages | 14 |
Journal | Journal of Clinical Medicine |
Volume | 10 |
Issue number | 21 |
Early online date | 20 Oct 2021 |
DOIs | |
Publication status | Published - 1 Nov 2021 |
Bibliographical note
Funding Information:The guideline development was partly funded by the Dutch Quality Fund for Medical Specialists for the Netherlands Society for Plastic and Reconstructive Surgery with co?funding from the Dutch Association for Oto?rhino?laryngology and Surgery of the Head and Neck, the Dutch Association of Orthodontists, the Dutch Scientific Association of Dentists, and the Dutch Association for Oral and Maxillofacial Surgery. Additional funding will be available to keep these CPGs up to date in the near future. The translation to English was supported by the European Reference Network for rare and/or complex craniofacial anomalies and ear, nose, and throat (ENT) disorders (www.ern?cranio.eu). No funding has been received to cover the article processing fee (which was waved).
Funding Information:
Funding: The guideline development was partly funded by the Dutch Quality Fund for Medical Specialists for the Netherlands Society for Plastic and Reconstructive Surgery with co‐funding from the Dutch Association for Oto‐rhino‐laryngology and Surgery of the Head and Neck, the Dutch Association of Orthodontists, the Dutch Scientific Association of Dentists, and the Dutch Association for Oral and Maxillofacial Surgery. Additional funding will be available to keep these CPGs up to date in the near future. The translation to English was supported by the European Reference Network for rare and/or complex craniofacial anomalies and ear, nose, and throat (ENT) disorders (www.ern‐cranio.eu). No funding has been received to cover the article processing fee (which was waved).
Publisher Copyright:
© 2021 by the authors. Licensee MDPI, Basel, Switzerland.
Funding
The guideline development was partly funded by the Dutch Quality Fund for Medical Specialists for the Netherlands Society for Plastic and Reconstructive Surgery with co?funding from the Dutch Association for Oto?rhino?laryngology and Surgery of the Head and Neck, the Dutch Association of Orthodontists, the Dutch Scientific Association of Dentists, and the Dutch Association for Oral and Maxillofacial Surgery. Additional funding will be available to keep these CPGs up to date in the near future. The translation to English was supported by the European Reference Network for rare and/or complex craniofacial anomalies and ear, nose, and throat (ENT) disorders (www.ern?cranio.eu). No funding has been received to cover the article processing fee (which was waved). Funding: The guideline development was partly funded by the Dutch Quality Fund for Medical Specialists for the Netherlands Society for Plastic and Reconstructive Surgery with co‐funding from the Dutch Association for Oto‐rhino‐laryngology and Surgery of the Head and Neck, the Dutch Association of Orthodontists, the Dutch Scientific Association of Dentists, and the Dutch Association for Oral and Maxillofacial Surgery. Additional funding will be available to keep these CPGs up to date in the near future. The translation to English was supported by the European Reference Network for rare and/or complex craniofacial anomalies and ear, nose, and throat (ENT) disorders (www.ern‐cranio.eu). No funding has been received to cover the article processing fee (which was waved).
Keywords
- Cleft lip, alveolus and palate
- Clinical practice guideline
- Quality of health care
- Recommendation clinical care
- Treatment