Clobenpropit analogs as dual activity ligands for the histamine H3 and H4 receptors: synthesis, pharmacological evaluation, and cross-target QSAR studies

H.D. Lim; E.P. Istyastono; A. van de Stolpe; G. Romeo; S. Gobbi; M. Schepers; R. Lahaye; W.M. Menge; O.P. Zuiderveld; A. Jongejan; R.A. Smits; R.A. Bakker; E.E. Haaksma; R. Leurs; I.J.P. de Esch

doi:10.1016/j.bmc.2009.04.007

Clobenpropit analogs as dual activity ligands for the histamine H3 and H4 receptors: synthesis, pharmacological evaluation, and cross-target QSAR studies

H.D. Lim, E.P. Istyastono, A. van de Stolpe, G. Romeo, S. Gobbi, M. Schepers, R. Lahaye, W.M. Menge, O.P. Zuiderveld, A. Jongejan, R.A. Smits, R.A. Bakker, E.E. Haaksma, R. Leurs, I.J.P. de Esch

Medicinal chemistry

Research output: Contribution to Journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	3987-94
Journal	Bioorganic and Medicinal Chemistry
Volume	17
Issue number	11
DOIs	https://doi.org/10.1016/j.bmc.2009.04.007
Publication status	Published - 2009

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10.1016/j.bmc.2009.04.007

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Lim, H. D., Istyastono, E. P., van de Stolpe, A., Romeo, G., Gobbi, S., Schepers, M., Lahaye, R., Menge, W. M., Zuiderveld, O. P., Jongejan, A., Smits, R. A., Bakker, R. A., Haaksma, E. E., Leurs, R., & de Esch, I. J. P. (2009). Clobenpropit analogs as dual activity ligands for the histamine H3 and H4 receptors: synthesis, pharmacological evaluation, and cross-target QSAR studies. Bioorganic and Medicinal Chemistry, 17(11), 3987-94. https://doi.org/10.1016/j.bmc.2009.04.007

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title = "Clobenpropit analogs as dual activity ligands for the histamine H3 and H4 receptors: synthesis, pharmacological evaluation, and cross-target QSAR studies",

author = "H.D. Lim and E.P. Istyastono and {van de Stolpe}, A. and G. Romeo and S. Gobbi and M. Schepers and R. Lahaye and W.M. Menge and O.P. Zuiderveld and A. Jongejan and R.A. Smits and R.A. Bakker and E.E. Haaksma and R. Leurs and {de Esch}, I.J.P.",

year = "2009",

doi = "10.1016/j.bmc.2009.04.007",

language = "English",

volume = "17",

pages = "3987--94",

journal = "Bioorganic and Medicinal Chemistry",

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Lim, HD, Istyastono, EP, van de Stolpe, A, Romeo, G, Gobbi, S, Schepers, M, Lahaye, R, Menge, WM, Zuiderveld, OP, Jongejan, A, Smits, RA, Bakker, RA, Haaksma, EE, Leurs, R & de Esch, IJP 2009, 'Clobenpropit analogs as dual activity ligands for the histamine H3 and H4 receptors: synthesis, pharmacological evaluation, and cross-target QSAR studies', Bioorganic and Medicinal Chemistry, vol. 17, no. 11, pp. 3987-94. https://doi.org/10.1016/j.bmc.2009.04.007

TY - JOUR

T1 - Clobenpropit analogs as dual activity ligands for the histamine H3 and H4 receptors: synthesis, pharmacological evaluation, and cross-target QSAR studies

AU - Lim, H.D.

AU - Istyastono, E.P.

AU - van de Stolpe, A.

AU - Romeo, G.

AU - Gobbi, S.

AU - Schepers, M.

AU - Lahaye, R.

AU - Menge, W.M.

AU - Zuiderveld, O.P.

AU - Jongejan, A.

AU - Smits, R.A.

AU - Bakker, R.A.

AU - Haaksma, E.E.

AU - Leurs, R.

AU - de Esch, I.J.P.

PY - 2009

Y1 - 2009

U2 - 10.1016/j.bmc.2009.04.007

DO - 10.1016/j.bmc.2009.04.007

M3 - Article

SN - 0968-0896

VL - 17

SP - 3987

EP - 3994

JO - Bioorganic and Medicinal Chemistry

JF - Bioorganic and Medicinal Chemistry

IS - 11

ER -