Abstract
The objective of this study is to obtain population level data about cognitive functions and their association with mental disorders. We here report factor analytic and psychometric findings of a neuropsychological test battery and examine the association of current and past mental disorders with cognitive function in a large nationwide population-based sample of 18- to 79-year-old adults in Germany (n = 3,667) participating in the mental health module of the German Health Interview and Examination Survey for Adults 2008–2011. Confirmatory factor analysis confirmed verbal memory and executive function factors. Older age was strongly associated with lower verbal memory and executive function and with higher vocabulary scores. After adjustment for age, sex, and education, rather modest decrements were found for verbal memory (β = −.118, p =.002) and executive functions (β = −.191, p <.001) in participants with any current mental disorder (n = 442) compared to those without (n = 3,201). Small decrements in memory (β = −.064, p =.031) and executive function (β = −.111, p <.001) were found in participants with any mental disorder in the last 12 months but not in those with past (fully or partially remitted) mental disorders, compared to participants without a history of mental disorder. More fine-grained analyses of these data will investigate the complex interplay between cognition, health behaviors, and specific mental and somatic diseases.
Original language | English |
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Article number | e1594 |
Pages (from-to) | 1-10 |
Number of pages | 10 |
Journal | International Journal of Methods in Psychiatric Research |
Volume | 27 |
Issue number | 1 |
Early online date | 6 Nov 2017 |
DOIs | |
Publication status | Published - Mar 2018 |
Funding
DEGS1 was funded primarily by the German Ministry of Health (Bundesministerium für Gesundheit [BMG]). Supplementary funding for DEGS1‐MH was provided by the Technische Universität Dresden (TUD) and by the Foundation for Mental Health (Stiftung Seelische Gesundheit) inaugurated by the German Association for Psychiatry, Psychotherapy, and Psychosomatics (Deutsche Gesellschaft für Psychiatrie und Psychotherapie, Psychosomatik und Nervenheilkunde [DGPPN]). The neuropsychological section was jointly developed and implemented by TUD (Frank Jacobi), Robert Koch Institute (RKI; Markus Busch), and the University of Bonn (Department of Psychiatry: Michael Wagner).
Funders | Funder number |
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DGPPN | |
Deutsche Gesellschaft für Psychiatrie und Psychotherapie, Psychosomatik und Nervenheilkunde | |
German Association for Psychiatry | |
German Ministry of Health | |
Stiftung Seelische Gesundheit | |
Technische Universität Dresden | |
Bundesministerium für Gesundheit | |
Fonds Psychische Gezondheid |
Keywords
- cognition
- epidemiology
- neuropsychology
- psychometrics