TY - JOUR
T1 - Cognitive mediation of panic reduction during an early intervention for panic
AU - Meulenbeek, P.
AU - Spinhoven, P.
AU - Smit, H.F.E.
AU - van Balkom, A.J.L.M.
AU - Cuijpers, P.
PY - 2010
Y1 - 2010
N2 - Objective: This study investigated cognitive mediation of improvement in panic disorder (PD) symptomatology during and after an early intervention for panic symptoms in subthreshold and mild PD. Method: We executed a pragmatic, pre-post, two-group, multi-site, randomized trial of an early intervention for panic symptoms, based on cognitive-behavioural therapy, vs. a wait-list control group in a sample of 217 participants with subthreshold PD or mild PD. Results: First, two of the three subscales of the mediator variable Panic Appraisal Inventory (PAI-anticipation and PAI-coping) significantly mediated residual change in PD symptomatology on the PD Severity Scale-Self Report. Second, preintervention to postintervention PAI-anticipation and PAI-coping change scores significantly predicted postintervention to follow-up change in PD symptomatology after controlling for other change scores. However, the converse association was also significant. Conclusion: The results suggest that changes in cognitions may mediate changes in PD symptomatology and that the process of change is circular. © 2010 John Wiley & Sons A/S.
AB - Objective: This study investigated cognitive mediation of improvement in panic disorder (PD) symptomatology during and after an early intervention for panic symptoms in subthreshold and mild PD. Method: We executed a pragmatic, pre-post, two-group, multi-site, randomized trial of an early intervention for panic symptoms, based on cognitive-behavioural therapy, vs. a wait-list control group in a sample of 217 participants with subthreshold PD or mild PD. Results: First, two of the three subscales of the mediator variable Panic Appraisal Inventory (PAI-anticipation and PAI-coping) significantly mediated residual change in PD symptomatology on the PD Severity Scale-Self Report. Second, preintervention to postintervention PAI-anticipation and PAI-coping change scores significantly predicted postintervention to follow-up change in PD symptomatology after controlling for other change scores. However, the converse association was also significant. Conclusion: The results suggest that changes in cognitions may mediate changes in PD symptomatology and that the process of change is circular. © 2010 John Wiley & Sons A/S.
U2 - 10.1111/j.1600-0447.2009.01530.x
DO - 10.1111/j.1600-0447.2009.01530.x
M3 - Article
SN - 0001-690X
VL - 122
SP - 20
EP - 29
JO - Acta psychiatrica scandinavica
JF - Acta psychiatrica scandinavica
IS - 1
ER -