TY - JOUR
T1 - Cognitive restructuring, behavioral activation and cognitive-behavioral therapy in the treatment of adult depression
T2 - A network meta-analysis
AU - Ciharova, Marketa
AU - Furukawa, Toshi A.
AU - Efthimiou, Orestis
AU - Karyotaki, Eirini
AU - Miguel, Clara
AU - Noma, Hisashi
AU - Cipriani, Andrea
AU - Riper, Heleen
AU - Cuijpers, Pim
N1 - Publisher Copyright:
© 2021 American Psychological Association
PY - 2021/6
Y1 - 2021/6
N2 - Objective: To examine if cognitive restructuring (CR), behavioral activation (BA), and cognitive-behavioral therapy (CBT) result in differential effects in the treatment of adult depression. Method: We extracted randomized controlled trials (RCTs) from a database updated yearly from PubMed, PsycINFO, Embase, and Cochrane Library. Network and pairwise meta-analyses were conducted to investigate the effects of CR, BA, and CBT delivered in a face-to-face individual format, compared with waiting list (WL) and care-as-usual (CAU), on adult depression. The primary outcome was a standardized mean difference (SMD) in posttreatment depression severity. Tolerability of treatments and depression severity at follow-up were also assessed. Results: A total of 45 studies with 3,382 participants were included. There was no evidence of a difference in effectiveness between CR, BA, and CBT. All three interventions were superior to CAU; SMD 0.57, 95% confidence interval [CI 0.08–1.07]; 0.52 [0.34–0.71]; 0.44 [0.28–0.60], respectively and WL 1.20 [0.69–1.70]; 1.15 [0.90–1.40]; 1.07 [0.87–1.26]. No difference in tolerability was found (risk ratio [RR] vs. CAU: 1.01 [0.04–22.81], 0.84 [0.63–1.11], and 0.96 [0.76–1.21], respectively). Metaregression and sensitivity analyses did not produce material differences. Conclusions: Results suggest that CR or BA alone and their combination (CBT) may be effective interventions in comparison to WL and CAU in the treatment of adult depression. There was no evidence suggesting differences in effectiveness among the three treatments. More research is needed to derive conclusions about the performance of CR. (PsycInfo Database Record (c) 2021 APA, all rights reserved)
AB - Objective: To examine if cognitive restructuring (CR), behavioral activation (BA), and cognitive-behavioral therapy (CBT) result in differential effects in the treatment of adult depression. Method: We extracted randomized controlled trials (RCTs) from a database updated yearly from PubMed, PsycINFO, Embase, and Cochrane Library. Network and pairwise meta-analyses were conducted to investigate the effects of CR, BA, and CBT delivered in a face-to-face individual format, compared with waiting list (WL) and care-as-usual (CAU), on adult depression. The primary outcome was a standardized mean difference (SMD) in posttreatment depression severity. Tolerability of treatments and depression severity at follow-up were also assessed. Results: A total of 45 studies with 3,382 participants were included. There was no evidence of a difference in effectiveness between CR, BA, and CBT. All three interventions were superior to CAU; SMD 0.57, 95% confidence interval [CI 0.08–1.07]; 0.52 [0.34–0.71]; 0.44 [0.28–0.60], respectively and WL 1.20 [0.69–1.70]; 1.15 [0.90–1.40]; 1.07 [0.87–1.26]. No difference in tolerability was found (risk ratio [RR] vs. CAU: 1.01 [0.04–22.81], 0.84 [0.63–1.11], and 0.96 [0.76–1.21], respectively). Metaregression and sensitivity analyses did not produce material differences. Conclusions: Results suggest that CR or BA alone and their combination (CBT) may be effective interventions in comparison to WL and CAU in the treatment of adult depression. There was no evidence suggesting differences in effectiveness among the three treatments. More research is needed to derive conclusions about the performance of CR. (PsycInfo Database Record (c) 2021 APA, all rights reserved)
KW - behavioral activation
KW - cognitive restructuring
KW - cognitive-behavioral therapy
KW - depression
KW - network meta-analysis
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U2 - 10.1037/ccp0000654
DO - 10.1037/ccp0000654
M3 - Article
C2 - 34264703
AN - SCOPUS:85111725690
SN - 0022-006X
VL - 89
SP - 563
EP - 574
JO - Journal of Consulting and Clinical Psychology
JF - Journal of Consulting and Clinical Psychology
IS - 6
ER -