Column liquid chromatography with diode laser-induced fluorescence detection of carboxylic acids after pre-column derivatization.

A.J.G. Mank, M.C. Beekman, N.H. Velthorst, U.A.T. Brinkman, H. Lingeman, C. Gooijer

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

Several pre-column approaches to fluorescence derivatisation of carboxylic acids, compatible with diode laser-induced fluorescence (DIO-LIF) detection, were compared. For this purpose red-absorbing labels containing hydrazide, bromoacetamide and iodoacetamide functionalities were studied. The sensitivity of DIO-LIF detection is illustrated by the (3-10) × 10
Original languageEnglish
Pages (from-to)209
JournalAnalytica Chimica Acta
Volume315
DOIs
Publication statusPublished - 1995

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