Common variants at 12q15 and 12q24 are associated with infant head circumference

H.R. Taal; B. St Pourcain; E. Thiering; S. Das; D.O. Mook-Kanamori; C.E.M. van Beijsterveldt; M.M. Groen-Blokhuis; J.J. Hottenga; C.M. Middeldorp; G. Willemsen; D.I. Boomsma; H. Hakonarson; G.D. Smith; J. Heinrich; M.-R. Jarvelin; V.W.V. Jaddoe

doi:10.1038/ng.2238

Common variants at 12q15 and 12q24 are associated with infant head circumference

H.R. Taal
, B. St Pourcain
, E. Thiering
, S. Das
, D.O. Mook-Kanamori
, C.E.M. van Beijsterveldt
, M.M. Groen-Blokhuis
, J.J. Hottenga
, C.M. Middeldorp
, G. Willemsen
, D.I. Boomsma
, H. Hakonarson
, G.D. Smith
, J. Heinrich
, M.-R. Jarvelin
, V.W.V. Jaddoe

Biological Psychology

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

To identify genetic variants associated with head circumference in infancy, we performed a meta-analysis of seven genome-wide association studies (GWAS) (N = 10,768 individuals of European ancestry enrolled in pregnancy and/or birth cohorts) and followed up three lead signals in six replication studies (combined N = 19,089). rs7980687 on chromosome 12q24 (P = 8.1 × 10

Original language	English
Pages (from-to)	532-538
Journal	Nature Genetics
Volume	44
Issue number	5
DOIs	https://doi.org/10.1038/ng.2238
Publication status	Published - 2012

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Cohort Studies

Netherlands Twin Register (NTR)

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10.1038/ng.2238

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Taal, H. R., St Pourcain, B., Thiering, E., Das, S., Mook-Kanamori, D. O., van Beijsterveldt, C. E. M., Groen-Blokhuis, M. M., Hottenga, J. J., Middeldorp, C. M., Willemsen, G., Boomsma, D. I., Hakonarson, H., Smith, G. D., Heinrich, J., Jarvelin, M.-R., & Jaddoe, V. W. V. (2012). Common variants at 12q15 and 12q24 are associated with infant head circumference. Nature Genetics, 44(5), 532-538. https://doi.org/10.1038/ng.2238

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abstract = "To identify genetic variants associated with head circumference in infancy, we performed a meta-analysis of seven genome-wide association studies (GWAS) (N = 10,768 individuals of European ancestry enrolled in pregnancy and/or birth cohorts) and followed up three lead signals in six replication studies (combined N = 19,089). rs7980687 on chromosome 12q24 (P = 8.1 × 10",

author = "H.R. Taal and \{St Pourcain\}, B. and E. Thiering and S. Das and D.O. Mook-Kanamori and \{van Beijsterveldt\}, C.E.M. and M.M. Groen-Blokhuis and J.J. Hottenga and C.M. Middeldorp and G. Willemsen and D.I. Boomsma and H. Hakonarson and G.D. Smith and J. Heinrich and M.-R. Jarvelin and V.W.V. Jaddoe",

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Taal, HR, St Pourcain, B, Thiering, E, Das, S, Mook-Kanamori, DO, van Beijsterveldt, CEM, Groen-Blokhuis, MM, Hottenga, JJ, Middeldorp, CM, Willemsen, G, Boomsma, DI, Hakonarson, H, Smith, GD, Heinrich, J, Jarvelin, M-R & Jaddoe, VWV 2012, 'Common variants at 12q15 and 12q24 are associated with infant head circumference', Nature Genetics, vol. 44, no. 5, pp. 532-538. https://doi.org/10.1038/ng.2238

TY - JOUR

T1 - Common variants at 12q15 and 12q24 are associated with infant head circumference

AU - Taal, H.R.

AU - St Pourcain, B.

AU - Thiering, E.

AU - Das, S.

AU - Mook-Kanamori, D.O.

AU - van Beijsterveldt, C.E.M.

AU - Groen-Blokhuis, M.M.

AU - Hottenga, J.J.

AU - Middeldorp, C.M.

AU - Willemsen, G.

AU - Boomsma, D.I.

AU - Hakonarson, H.

AU - Smith, G.D.

AU - Heinrich, J.

AU - Jarvelin, M.-R.

AU - Jaddoe, V.W.V.

PY - 2012

Y1 - 2012

N2 - To identify genetic variants associated with head circumference in infancy, we performed a meta-analysis of seven genome-wide association studies (GWAS) (N = 10,768 individuals of European ancestry enrolled in pregnancy and/or birth cohorts) and followed up three lead signals in six replication studies (combined N = 19,089). rs7980687 on chromosome 12q24 (P = 8.1 × 10

AB - To identify genetic variants associated with head circumference in infancy, we performed a meta-analysis of seven genome-wide association studies (GWAS) (N = 10,768 individuals of European ancestry enrolled in pregnancy and/or birth cohorts) and followed up three lead signals in six replication studies (combined N = 19,089). rs7980687 on chromosome 12q24 (P = 8.1 × 10

U2 - 10.1038/ng.2238

DO - 10.1038/ng.2238

M3 - Article

SN - 1061-4036

VL - 44

SP - 532

EP - 538

JO - Nature Genetics

JF - Nature Genetics

IS - 5

ER -

Common variants at 12q15 and 12q24 are associated with infant head circumference

Abstract

UN SDGs

Cohort Studies

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