TY - JOUR
T1 - Comprehensive two-dimensional gas chromatography with time-of-flight mass spectrometric detection for the trace analysis of flavour compounds in food
AU - Adahchour, M.
AU - van Stee, L.L.P.
AU - Beens, J.
AU - Vreuls, R.J.J.
AU - van Batenburg, M.F.
AU - Brinkman, U.A.T.
PY - 2003
Y1 - 2003
N2 - The practicability and potential of comprehensive two-dimensional gas chromatography coupled to time-of-flight mass spectrometry (GC×GC-TOF-MS) for the analysis of complex flavour mixtures in food were studied. With the determination of key flavour targets in dairy samples as an example, it was demonstrated that GC×GC dramatically improves the separation. As a consequence, identification and, more importantly, quantification down to the ng/g level can be performed more reliably: background interferences largely disappear. Next to the peak table generated from the GC-TOF-MS software after data processing, the additional use of well-ordered patterns in the 2D-plane and information from second-dimension retention times can substantially help the identification of unknowns. The technique was successfully used for an evaluation of extraction techniques and the characterisation of different types of samples. © 2003 Published by Elsevier B.V.
AB - The practicability and potential of comprehensive two-dimensional gas chromatography coupled to time-of-flight mass spectrometry (GC×GC-TOF-MS) for the analysis of complex flavour mixtures in food were studied. With the determination of key flavour targets in dairy samples as an example, it was demonstrated that GC×GC dramatically improves the separation. As a consequence, identification and, more importantly, quantification down to the ng/g level can be performed more reliably: background interferences largely disappear. Next to the peak table generated from the GC-TOF-MS software after data processing, the additional use of well-ordered patterns in the 2D-plane and information from second-dimension retention times can substantially help the identification of unknowns. The technique was successfully used for an evaluation of extraction techniques and the characterisation of different types of samples. © 2003 Published by Elsevier B.V.
U2 - 10.1016/S0021-9673(03)01131-2
DO - 10.1016/S0021-9673(03)01131-2
M3 - Article
SN - 0021-9673
VL - 1019
SP - 157
EP - 172
JO - Journal of chromatography A
JF - Journal of chromatography A
IS - 1-2
ER -