TY - JOUR
T1 - Comprehensive two-dimensional gas chromatograpy with time-of-flight mass spectrometric detection applied to the determination of pesticides in food extracts
AU - Dalluge, J.
AU - van Rijn, M.J.
AU - Beens, J.
AU - Vreuls, R.J.J.
AU - Brinkman, U.A.T.
PY - 2002
Y1 - 2002
N2 - The separation provided by conventional gas chromatography (1D-GC) can be significantly enhanced by using comprehensive two-dimensional GC (GC×GC) instead. Combination with mass spectrometric detection is desirable for unambiguous confirmation of target compounds and the provisional identification of unknowns. A GC×GC system using a cryogenic modulator was coupled to a time-of-flight mass spectrometric (TOF MS) detector. With the determination of pesticides in vegetable extracts as an example, it was demonstrated that GC×GC improves the separation dramatically. All 58 pesticides of interest could be identified using their full-scan mass spectra, which was not possible when using 1D-GC-TOF MS. In addition, the high scan speed of the TOF MS allowed the deconvolution of compounds partly co-eluting in GC×GC. © 2002 Elsevier Science B.V. All rights reserved.
AB - The separation provided by conventional gas chromatography (1D-GC) can be significantly enhanced by using comprehensive two-dimensional GC (GC×GC) instead. Combination with mass spectrometric detection is desirable for unambiguous confirmation of target compounds and the provisional identification of unknowns. A GC×GC system using a cryogenic modulator was coupled to a time-of-flight mass spectrometric (TOF MS) detector. With the determination of pesticides in vegetable extracts as an example, it was demonstrated that GC×GC improves the separation dramatically. All 58 pesticides of interest could be identified using their full-scan mass spectra, which was not possible when using 1D-GC-TOF MS. In addition, the high scan speed of the TOF MS allowed the deconvolution of compounds partly co-eluting in GC×GC. © 2002 Elsevier Science B.V. All rights reserved.
U2 - 10.1016/S0021-9673(01)01324-3
DO - 10.1016/S0021-9673(01)01324-3
M3 - Article
VL - 965
SP - 207
EP - 217
JO - Journal of chromatography A
JF - Journal of chromatography A
SN - 0021-9673
IS - 1-2
ER -