Computational quantification of metabolic fluxes from a single isotope snapshot: application to an animal biopsy.

T.W. Binsl, D.J.C. Alders, J. Heringa, A.B.J. Groeneveld, J.H.G.M. van Beek

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

Motivation: Quantitative determination of metabolic fluxes in single tissue biopsies is difficult. We report a novel analysis approach and software package for in vivo flux quantification using stable isotope labeling. Results: We developed a protocol based on brief, timed infusion of
Original languageEnglish
Pages (from-to)653-660
JournalBioinformatics
Volume26
Issue number5
DOIs
Publication statusPublished - 2010

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