Computational quantification of metabolic fluxes from a single isotope snapshot: application to an animal biopsy.

T.W. Binsl; D.J.C. Alders; J. Heringa; A.B.J. Groeneveld; J.H.G.M. van Beek

doi:10.1093/bioinformatics/btq018

Computational quantification of metabolic fluxes from a single isotope snapshot: application to an animal biopsy.

T.W. Binsl
, D.J.C. Alders
, J. Heringa
, A.B.J. Groeneveld
, J.H.G.M. van Beek

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

Motivation: Quantitative determination of metabolic fluxes in single tissue biopsies is difficult. We report a novel analysis approach and software package for in vivo flux quantification using stable isotope labeling. Results: We developed a protocol based on brief, timed infusion of

Original language	English
Pages (from-to)	653-660
Journal	Bioinformatics
Volume	26
Issue number	5
DOIs	https://doi.org/10.1093/bioinformatics/btq018
Publication status	Published - 2010

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10.1093/bioinformatics/btq018

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title = "Computational quantification of metabolic fluxes from a single isotope snapshot: application to an animal biopsy.",

abstract = "Motivation: Quantitative determination of metabolic fluxes in single tissue biopsies is difficult. We report a novel analysis approach and software package for in vivo flux quantification using stable isotope labeling. Results: We developed a protocol based on brief, timed infusion of",

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AU - Alders, D.J.C.

AU - Heringa, J.

AU - Groeneveld, A.B.J.

AU - van Beek, J.H.G.M.

PY - 2010

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DO - 10.1093/bioinformatics/btq018

M3 - Article

SN - 1367-4803

VL - 26

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JO - Bioinformatics

JF - Bioinformatics

IS - 5

ER -

Computational quantification of metabolic fluxes from a single isotope snapshot: application to an animal biopsy.

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