Computational Study on the Anomalous Fluorescence Behavior of Isoflavones

S.M. Beyhan, A.W. Gotz, F. Ariese, L. Visscher, C. Gooijer

Research output: Contribution to JournalArticleAcademicpeer-review


Isoflavones are known to show fluorescence with intensities that depend strongly on the solvent properties and exhibit Stokes' shifts as large as 1.4 eV. While some of this behavior can be explained by (excited state) deprotonation, this mechanism does not apply for all isoflavones. The aim of this study is to computationally and experimentally investigate the reasons for this anomalous behavior of neutral isoflavones, taking the daidzein molecule as a model compound. We find that the absence in fluorescence in aprotic solvents and the weak fluorescence in protic solvents can be explained by a change of order of the lowest singlet states in which a fluorescent charge-transfer state lies below the nonfluorescent locally excited state in water but not in acetonitrile. The large Stokes' shift is partly due to a significant rotation among the chromone-phenyl bond in the excited state. © 2011 American Chemical Society.
Original languageEnglish
Pages (from-to)1493-1499
JournalJournal of Physical Chemistry A
Issue number9
Publication statusPublished - 2011


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