Constitutively active mutants of the histamine H1 receptor suggest a conserved hydrophobic asparagine-cage that constrains the activation of class A G protein-coupled receptors

R.A. Bakker, A. Jongejan, K. Sansuk, U. Hacksell, H. Timmerman, M.R. Brann, D.M. Weiner, L.M. Pardo, R. Leurs

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

The aim of this study was to create and characterize constitutively active mutant (CAM) histamine H
Original languageEnglish
Pages (from-to)94-103
JournalMolecular Pharmacology
Volume73
Issue number1
DOIs
Publication statusPublished - 2008

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