The authors regret that in Fig. 1 the letters indicating the enzymes involved in the reactions were not added to the arrows. A corrected Figure is shown below. [Figure presented] Fig. 1. Regioselective GSH-conjugation of trichloroethylene (TCE) and subsequent processing to corresponding mercapturic acids (N-acetylcysteine S-conjugates) and beta-lyase-dependent bioactivation of cysteine S-conjugates to reactive products. Enzymes involved: a. glutathione S-transferases; b. gamma-glutamyltransferase; c. cysteinyl-glycine dipeptidase; d. cysteine conjugate beta-lyase; e. cysteine conjugate N-acetyltransferase; f. aminoacylase. Formation of sulfoxides of mercapturic acids is not shown to avoid an overcomplicated figure. The authors would like to apologise for any inconvenience caused.
Bibliographical notePublisher Copyright:
© 2021 The Author(s)
Copyright 2021 Elsevier B.V., All rights reserved.
Corrigendum to “Bioactivation of trichloroethylene to three regioisomeric glutathione conjugates by liver fractions and recombinant human glutathione transferases: Species differences and implications for human risk assessment” [Toxicol. Lett. 341 (2021) 94–106] S0378427421000308)(10.1016/j.toxlet.2021.01.021.