Corrigendum to “Bioactivation of trichloroethylene to three regioisomeric glutathione conjugates by liver fractions and recombinant human glutathione transferases: Species differences and implications for human risk assessment” [Toxicol. Lett. 341 (2021) 94–106]

Liliana Capinha, Paul Jennings, Jan N.M. Commandeur*

*Corresponding author for this work

Research output: Contribution to JournalErratumAcademic

Abstract

The authors regret that in Fig. 1 the letters indicating the enzymes involved in the reactions were not added to the arrows. A corrected Figure is shown below. [Figure presented] Fig. 1. Regioselective GSH-conjugation of trichloroethylene (TCE) and subsequent processing to corresponding mercapturic acids (N-acetylcysteine S-conjugates) and beta-lyase-dependent bioactivation of cysteine S-conjugates to reactive products. Enzymes involved: a. glutathione S-transferases; b. gamma-glutamyltransferase; c. cysteinyl-glycine dipeptidase; d. cysteine conjugate beta-lyase; e. cysteine conjugate N-acetyltransferase; f. aminoacylase. Formation of sulfoxides of mercapturic acids is not shown to avoid an overcomplicated figure. The authors would like to apologise for any inconvenience caused.

Original languageEnglish
Pages (from-to)67-68
Number of pages2
JournalToxicology Letters
Volume343
DOIs
Publication statusPublished - 1 Jun 2021

Bibliographical note

Publisher Copyright:
© 2021 The Author(s)

Copyright:
Copyright 2021 Elsevier B.V., All rights reserved.

Corrigendum to “Bioactivation of trichloroethylene to three regioisomeric glutathione conjugates by liver fractions and recombinant human glutathione transferases: Species differences and implications for human risk assessment” [Toxicol. Lett. 341 (2021) 94–106] S0378427421000308)(10.1016/j.toxlet.2021.01.021.

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