Cortical changes in complex regional pain syndrome (CRPS)

C.M. Swart, J.F. Stins, P.J. Beek

    Research output: Contribution to JournalArticleAcademicpeer-review

    Abstract

    Recent research suggests that changes in cortical structures can contribute to the pathophysiology of Complex Regional Pain Syndrome (CRPS). This review provides an overview of studies showing cortical involvement in CRPS, including mislocalizations of tactile stimuli, changes in size and organization of the somatosensory map, changes in motor cortex representation and body perception disturbances. In addition, we review experimental treatment approaches, such as mirror therapy and motor imagery programs, aimed at restoring the integrity of neural processing in the sensory-motor cortex in individuals with CRPS. The intervention effects are promising and can be theoretically motivated on the basis of established principles of neural organization, although important questions concerning the precise neural mechanisms of action remain unanswered. © 2008 European Federation of International Association for the Study of Pain Chapters.
    Original languageEnglish
    Pages (from-to)902-907
    JournalEuropean Journal of Pain
    Volume13
    Issue number9
    DOIs
    Publication statusPublished - 2009

    Fingerprint

    Complex Regional Pain Syndromes
    Body Image
    Imagery (Psychotherapy)
    Motor Cortex
    Touch
    Therapeutics
    Research

    Cite this

    @article{f3218a2a528b4d36a6debf4d11a5b334,
    title = "Cortical changes in complex regional pain syndrome (CRPS)",
    abstract = "Recent research suggests that changes in cortical structures can contribute to the pathophysiology of Complex Regional Pain Syndrome (CRPS). This review provides an overview of studies showing cortical involvement in CRPS, including mislocalizations of tactile stimuli, changes in size and organization of the somatosensory map, changes in motor cortex representation and body perception disturbances. In addition, we review experimental treatment approaches, such as mirror therapy and motor imagery programs, aimed at restoring the integrity of neural processing in the sensory-motor cortex in individuals with CRPS. The intervention effects are promising and can be theoretically motivated on the basis of established principles of neural organization, although important questions concerning the precise neural mechanisms of action remain unanswered. {\circledC} 2008 European Federation of International Association for the Study of Pain Chapters.",
    author = "C.M. Swart and J.F. Stins and P.J. Beek",
    year = "2009",
    doi = "10.1016/j.ejpain.2008.11.010",
    language = "English",
    volume = "13",
    pages = "902--907",
    journal = "European Journal of Pain",
    issn = "1090-3801",
    publisher = "W.B. Saunders Ltd",
    number = "9",

    }

    Cortical changes in complex regional pain syndrome (CRPS). / Swart, C.M.; Stins, J.F.; Beek, P.J.

    In: European Journal of Pain, Vol. 13, No. 9, 2009, p. 902-907.

    Research output: Contribution to JournalArticleAcademicpeer-review

    TY - JOUR

    T1 - Cortical changes in complex regional pain syndrome (CRPS)

    AU - Swart, C.M.

    AU - Stins, J.F.

    AU - Beek, P.J.

    PY - 2009

    Y1 - 2009

    N2 - Recent research suggests that changes in cortical structures can contribute to the pathophysiology of Complex Regional Pain Syndrome (CRPS). This review provides an overview of studies showing cortical involvement in CRPS, including mislocalizations of tactile stimuli, changes in size and organization of the somatosensory map, changes in motor cortex representation and body perception disturbances. In addition, we review experimental treatment approaches, such as mirror therapy and motor imagery programs, aimed at restoring the integrity of neural processing in the sensory-motor cortex in individuals with CRPS. The intervention effects are promising and can be theoretically motivated on the basis of established principles of neural organization, although important questions concerning the precise neural mechanisms of action remain unanswered. © 2008 European Federation of International Association for the Study of Pain Chapters.

    AB - Recent research suggests that changes in cortical structures can contribute to the pathophysiology of Complex Regional Pain Syndrome (CRPS). This review provides an overview of studies showing cortical involvement in CRPS, including mislocalizations of tactile stimuli, changes in size and organization of the somatosensory map, changes in motor cortex representation and body perception disturbances. In addition, we review experimental treatment approaches, such as mirror therapy and motor imagery programs, aimed at restoring the integrity of neural processing in the sensory-motor cortex in individuals with CRPS. The intervention effects are promising and can be theoretically motivated on the basis of established principles of neural organization, although important questions concerning the precise neural mechanisms of action remain unanswered. © 2008 European Federation of International Association for the Study of Pain Chapters.

    U2 - 10.1016/j.ejpain.2008.11.010

    DO - 10.1016/j.ejpain.2008.11.010

    M3 - Article

    VL - 13

    SP - 902

    EP - 907

    JO - European Journal of Pain

    JF - European Journal of Pain

    SN - 1090-3801

    IS - 9

    ER -