Abstract
Objectives: To adequately monitor the course of cognitive functioning in persons with moderate to severe dementia, relevant cognitive tests for the advanced dementia stages are needed. We examined the ability of a test developed for the advanced dementia stages, the Severe Impairment Battery Short version (SIB-S), to measure cognitive change over time. Second, we examined type of memory impairment measured with the SIB-S in different dementia stages. Methods: Participants were institutionalized persons with moderate to severe dementia (N = 217). The SIB-S was administered at 6-month intervals during a 2-year period. Dementia severity at baseline was classified according to Global Deterioration Scale criteria. We used mixed models to evaluate the course of SIB-S total and domain scores, and whether dementia stage at baseline affected these courses. Results: SIB-S total scores declined significantly over time, and the course of decline differed significantly between dementia stages at baseline. Persons with moderately severe dementia declined faster in mean SIB-S total scores than persons with moderate or severe dementia. Between persons with moderate and moderately severe dementia, there was only a difference in the rate of decline of semantic items, but not episodic and non-semantic items. Conclusions: Although modest floor and slight ceiling effects were noted in severe and milder cases, respectively, the SIB-S proved to be one of few available adequate measures of cognitive change in institutionalized persons with moderate to severe dementia. (JINS, 2019, 25, 204-214).
| Language | English |
|---|---|
| Pages | 204-214 |
| Number of pages | 11 |
| Journal | Journal of the International Neuropsychological Society |
| Volume | 25 |
| Issue number | 2 |
| Early online date | 20 Nov 2018 |
| DOIs | |
| Publication status | Published - Feb 2019 |
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Keywords
- Cognition
- Cognitive decline
- Dementia
- Dementia stages
- Institutionalization
- Longitudinal studies
- Neuropsychological tests
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Course of Cognitive Functioning in Institutionalized Persons with Moderate to Severe Dementia : Evidence from the Severe Impairment Battery Short Version. / Wolf, Evelien T.; Weeda, Wouter D.; Wetzels, Roland B.; De Jonghe, Jos F.M.; Koopmans, Raymond C.T.M.
In: Journal of the International Neuropsychological Society, Vol. 25, No. 2, 02.2019, p. 204-214.Research output: Contribution to Journal › Article › Academic › peer-review
TY - JOUR
T1 - Course of Cognitive Functioning in Institutionalized Persons with Moderate to Severe Dementia
T2 - Journal of the International Neuropsychological Society
AU - Wolf, Evelien T.
AU - Weeda, Wouter D.
AU - Wetzels, Roland B.
AU - De Jonghe, Jos F.M.
AU - Koopmans, Raymond C.T.M.
PY - 2019/2
Y1 - 2019/2
N2 - Objectives: To adequately monitor the course of cognitive functioning in persons with moderate to severe dementia, relevant cognitive tests for the advanced dementia stages are needed. We examined the ability of a test developed for the advanced dementia stages, the Severe Impairment Battery Short version (SIB-S), to measure cognitive change over time. Second, we examined type of memory impairment measured with the SIB-S in different dementia stages. Methods: Participants were institutionalized persons with moderate to severe dementia (N = 217). The SIB-S was administered at 6-month intervals during a 2-year period. Dementia severity at baseline was classified according to Global Deterioration Scale criteria. We used mixed models to evaluate the course of SIB-S total and domain scores, and whether dementia stage at baseline affected these courses. Results: SIB-S total scores declined significantly over time, and the course of decline differed significantly between dementia stages at baseline. Persons with moderately severe dementia declined faster in mean SIB-S total scores than persons with moderate or severe dementia. Between persons with moderate and moderately severe dementia, there was only a difference in the rate of decline of semantic items, but not episodic and non-semantic items. Conclusions: Although modest floor and slight ceiling effects were noted in severe and milder cases, respectively, the SIB-S proved to be one of few available adequate measures of cognitive change in institutionalized persons with moderate to severe dementia. (JINS, 2019, 25, 204-214).
AB - Objectives: To adequately monitor the course of cognitive functioning in persons with moderate to severe dementia, relevant cognitive tests for the advanced dementia stages are needed. We examined the ability of a test developed for the advanced dementia stages, the Severe Impairment Battery Short version (SIB-S), to measure cognitive change over time. Second, we examined type of memory impairment measured with the SIB-S in different dementia stages. Methods: Participants were institutionalized persons with moderate to severe dementia (N = 217). The SIB-S was administered at 6-month intervals during a 2-year period. Dementia severity at baseline was classified according to Global Deterioration Scale criteria. We used mixed models to evaluate the course of SIB-S total and domain scores, and whether dementia stage at baseline affected these courses. Results: SIB-S total scores declined significantly over time, and the course of decline differed significantly between dementia stages at baseline. Persons with moderately severe dementia declined faster in mean SIB-S total scores than persons with moderate or severe dementia. Between persons with moderate and moderately severe dementia, there was only a difference in the rate of decline of semantic items, but not episodic and non-semantic items. Conclusions: Although modest floor and slight ceiling effects were noted in severe and milder cases, respectively, the SIB-S proved to be one of few available adequate measures of cognitive change in institutionalized persons with moderate to severe dementia. (JINS, 2019, 25, 204-214).
KW - Cognition
KW - Cognitive decline
KW - Dementia
KW - Dementia stages
KW - Institutionalization
KW - Longitudinal studies
KW - Neuropsychological tests
UR - http://www.scopus.com/inward/record.url?scp=85056834216&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85056834216&partnerID=8YFLogxK
U2 - 10.1017/S1355617718000991
DO - 10.1017/S1355617718000991
M3 - Article
VL - 25
SP - 204
EP - 214
JO - Journal of the International Neuropsychological Society
JF - Journal of the International Neuropsychological Society
SN - 1355-6177
IS - 2
ER -