Cultured rat striatal and cortcal astrocytes protect mesencephalic dopaminergic neurons against hydrogen peroxide toxicity independent of their effect on neuronal development.

C.H. Langeveld; E. Schepens; C.A.M. Jongenelen; J.C. Stoof; A. Bast; B. Drukarch

doi:10.1016/0304-3940(95)11596-O

Cultured rat striatal and cortcal astrocytes protect mesencephalic dopaminergic neurons against hydrogen peroxide toxicity independent of their effect on neuronal development.

C.H. Langeveld
, E. Schepens
, C.A.M. Jongenelen
, J.C. Stoof
, A. Bast
, B. Drukarch

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

Reactive oxygen species (ROS), including hydrogen peroxide, are supposed to be involved in the degeneration of dopaminergic neurons in Parkinson's disease. The potential role of astrocytes against neurotoxic effects of ROS was studied in cocultures of rat mesencephalic neurons and rat striatal or cortical astrocytes. Neuronal [

Original language	English
Pages (from-to)	13-16
Journal	Neuroscience Letters
Volume	192
DOIs	https://doi.org/10.1016/0304-3940(95)11596-O
Publication status	Published - 1995

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10.1016/0304-3940(95)11596-O

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title = "Cultured rat striatal and cortcal astrocytes protect mesencephalic dopaminergic neurons against hydrogen peroxide toxicity independent of their effect on neuronal development.",

abstract = "Reactive oxygen species (ROS), including hydrogen peroxide, are supposed to be involved in the degeneration of dopaminergic neurons in Parkinson's disease. The potential role of astrocytes against neurotoxic effects of ROS was studied in cocultures of rat mesencephalic neurons and rat striatal or cortical astrocytes. Neuronal [",

author = "C.H. Langeveld and E. Schepens and C.A.M. Jongenelen and J.C. Stoof and A. Bast and B. Drukarch",

year = "1995",

doi = "10.1016/0304-3940(95)11596-O",

language = "English",

volume = "192",

pages = "13--16",

journal = "Neuroscience Letters",

issn = "0304-3940",

publisher = "Elsevier Ireland Ltd",

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TY - JOUR

T1 - Cultured rat striatal and cortcal astrocytes protect mesencephalic dopaminergic neurons against hydrogen peroxide toxicity independent of their effect on neuronal development.

AU - Langeveld, C.H.

AU - Schepens, E.

AU - Jongenelen, C.A.M.

AU - Stoof, J.C.

AU - Bast, A.

AU - Drukarch, B.

PY - 1995

Y1 - 1995

N2 - Reactive oxygen species (ROS), including hydrogen peroxide, are supposed to be involved in the degeneration of dopaminergic neurons in Parkinson's disease. The potential role of astrocytes against neurotoxic effects of ROS was studied in cocultures of rat mesencephalic neurons and rat striatal or cortical astrocytes. Neuronal [

AB - Reactive oxygen species (ROS), including hydrogen peroxide, are supposed to be involved in the degeneration of dopaminergic neurons in Parkinson's disease. The potential role of astrocytes against neurotoxic effects of ROS was studied in cocultures of rat mesencephalic neurons and rat striatal or cortical astrocytes. Neuronal [

U2 - 10.1016/0304-3940(95)11596-O

DO - 10.1016/0304-3940(95)11596-O

M3 - Article

SN - 0304-3940

VL - 192

SP - 13

EP - 16

JO - Neuroscience Letters

JF - Neuroscience Letters

ER -

Cultured rat striatal and cortcal astrocytes protect mesencephalic dopaminergic neurons against hydrogen peroxide toxicity independent of their effect on neuronal development.

Abstract

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