Current and Potential Applications of Monoterpenes and Their Derivatives in Oral Health Care

Wiktoria Potocka*, Zainab Assy, Floris J. Bikker, Marja L. Laine

*Corresponding author for this work

Research output: Contribution to JournalReview articleAcademicpeer-review

Abstract

Plant products have been employed in medicine for centuries. As the world becomes more health-conscious, there is a growing interest in natural and minimally processed products for oral health care. This has led to an increase in research into the bioactive compounds found in plant products, particularly monoterpenes. Monoterpenes are known to have beneficial biological properties, but the specific mechanisms by which they exert their effects are not yet fully understood. Despite this, some monoterpenes are already being used in oral health care. For example, thymol, which has antibacterial properties, is an ingredient in varnish used for caries prevention. In addition to this, monoterpenes have also demonstrated antifungal, antiviral, and anti-inflammatory properties, making them versatile for various applications. As research continues, there is potential for even more discoveries regarding the benefits of monoterpenes in oral health care. This narrative literature review gives an overview of the biological properties and current and potential applications of selected monoterpenes and their derivatives in oral health care. These compounds demonstrate promising potential for future medical development, and their applications in future research are expected to expand.

Original languageEnglish
Article number7178
Pages (from-to)1-26
Number of pages26
JournalMolecules
Volume28
Issue number20
DOIs
Publication statusPublished - 2 Oct 2023

Bibliographical note

Funding Information:
This research was partly funded by the Nederlandse Organisatie voor Wetenschappelijk Onderzoek/Netherlands Organization for Applied Scientific research (NWO) grant number 19217. The APC was funded by the NWO.

Publisher Copyright:
© 2023 by the authors.

Funding

This research was partly funded by the Nederlandse Organisatie voor Wetenschappelijk Onderzoek/Netherlands Organization for Applied Scientific research (NWO) grant number 19217. The APC was funded by the NWO.

Keywords

  • dentistry
  • monoterpene
  • monoterpenoid
  • oral health
  • plant oil
  • plant product
  • terpene
  • volatile oil

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