CYP 2D6 Binding Affinity Predictions Using Multiple Ligand and Protein Conformations

Biochemistry, Genetics and Molecular Biology

• Binding Affinity 100%
• Protein Conformation 100%
• Dynamics 50%
• Ligand Binding 50%
• Protein Ligand 50%
• Enzyme Binding 50%
• Isoform 25%
• Computer Model 25%
• Thiourea 25%

Neuroscience

• Cytochrome P450 100%
• Binding Affinity 100%
• Protein Conformation 100%
• Ligand Binding 33%
• Enzyme Binding 33%
• Thiourea 16%

Chemistry

• Kd 100%
• Cytochrome P450 100%
• Thiourea 16%
• Free Energy of Binding 16%
• Xenobiotic Agent 16%