Deficits in visuo-spatial working memory, inhibition and oculomotor control in boys with ADHD and their non-affected brothers

N.N.J. Rommelse, S. van der Stigchel, J. Witlox, C.J.A. Geldof, J.B. Deijen, J. Theeuwes, J. Oosterlaan, J.A. Sergeant

Research output: Contribution to JournalArticleAcademicpeer-review

199 Downloads (Pure)

Abstract

Few studies have assessed visuo-spatial working memory and inhibition in attention-deficit/hyperactivity disorder (ADHD) by recording saccades and consequently little additional knowledge has been gathered on oculomotor functioning in ADHD. Moreover, this is the first study to report the performance of non-affected siblings of children with ADHD, which may shed light on the familiality of deficits. A total of 14 boys with ADHD, 18 non-affected brothers, and 15 control boys aged 7-14 years, were administered a memory-guided saccade task with delays of three and seven seconds. Familial deficits were found in accuracy of visuo-spatial working memory, percentage of anticipatory saccades, and tendency to overshoot saccades relative to controls. These findings suggest memory-guided saccade deficits may relate to a familial predisposition for ADHD. © 2008 Springer-Verlag.
Original languageEnglish
Pages (from-to)249–260
Number of pages12
JournalJournal of Neural Transmission
Volume115
Issue number2
Early online date8 Feb 2008
DOIs
Publication statusPublished - Feb 2008

Fingerprint

Dive into the research topics of 'Deficits in visuo-spatial working memory, inhibition and oculomotor control in boys with ADHD and their non-affected brothers'. Together they form a unique fingerprint.

Cite this