Abstract
The number of metals to which humans are exposed has sharply increased during the 20th century. In dentistry, usually alloys are a mixture of two or more metals. Classification of dental alloys has recently been renewed after the introduction of titanium (Ti) and Ti alloys. This chapter describes the effects of a broad panel of orally applied metals and alloys on the human immune system with a focus on innate responsiveness and early inflammatory events. Noble metal-based alloys have the longest history of use in dentistry. High noble and noble alloys, in particular gold, platinum and palladium, were increasingly used because of their physical and mechanical properties. Despite the fact that the gastrointestinal tract is known as a tolerogenic entry route for foreign proteins and chemicals, oral exposure to dental alloys has often been associated with local or even systemic adverse reactions.
Original language | English |
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Title of host publication | Immunology for Dentistry |
Editors | Mohammad Tariqur Rahman, Wim Teughels, Richard J. Lamont |
Publisher | Wiley |
Chapter | 12 |
Pages | 165-186 |
Number of pages | 22 |
ISBN (Electronic) | 9781119893035 |
ISBN (Print) | 9781119893004 |
DOIs | |
Publication status | Published - 2023 |
Bibliographical note
Publisher Copyright:© 2023 John Wiley & Sons Ltd. All rights reserved.
Keywords
- Dental alloys
- Gastrointestinal tract
- Human immune system
- Innate responsiveness
- Mechanical properties
- Noble alloys
- Systemic adverse reactions
- Titanium alloys